Zantac 150 and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zantac 150 (ranitidine hydrochloride) and Digoxin (digoxin). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zantac 150 and Digoxin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Zantac 150?

Zantac 150 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,519 Zantac 150 users. Check the latest studies of Zantac 150.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 05, 2026

31 people who take Zantac 150 and Digoxin together, and have interactions are studied.

Zantac 150 and Digoxin drug interactions.

What are the common drug interactions of Zantac 150 and Digoxin, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal pain (kidney pain)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthma
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Depression
Haemorrhagic cerebral infarction (brain stroke with bleeding)
Multiple injuries

male:

Chronic kidney disease
Weight decreased
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Blood chloride increased
Blood pressure diastolic decreased
Blood sodium decreased
Body temperature decreased
Cardiovascular disorder (heart diseases)
Disease recurrence
Drug toxicity

What are the common drug interactions of Zantac 150 and Digoxin, by age (0-1 to 60+)? *:

0-1:

Apnoea (suspension of external breathing)
Vomiting

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal injury (kidney injury)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Depression
Stress
Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

Chronic kidney disease
Renal pain (kidney pain)
Decreased appetite
Haematocrit decreased
Haemorrhagic cerebral infarction (brain stroke with bleeding)
Multiple injuries
Pneumonia
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Syncope (loss of consciousness with an inability to maintain postural tone)
Thirst

What are the existing conditions these people have? *

High Blood Cholesterol: 11 people, 35.48%
High Blood Pressure: 8 people, 25.81%
Pain: 7 people, 22.58%
Indigestion: 5 people, 16.13%
Diabetes: 3 people, 9.68%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 9.68%
Oedema (fluid collection in tissue): 3 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.68%
Depression: 3 people, 9.68%
Thyroid Diseases: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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