Zefazone and Pepcid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zefazone (cefmetazole sodium) and Pepcid (famotidine). Common drug interactions include angina pectoris among females and disseminated intravascular coagulation among males.

The phase IV clinical study analyzes what interactions people have when they take Zefazone and Pepcid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Zefazone?

Zefazone has active ingredients of cefmetazole sodium. eHealthMe is studying from 29 Zefazone users. Check the latest studies of Zefazone.

What is Pepcid?

Pepcid has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 55,774 Pepcid users. Check the latest studies of Pepcid.

On Jul, 23, 2026

14 people who take Zefazone and Pepcid together, and have interactions are studied.

What are the common drug interactions of Zefazone and Pepcid, by gender? *:

female:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Electrolyte imbalance
Hypokalaemia (low potassium)
Leukopenia (less number of white blood cells in blood)
Peritoneal abscess
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Thrombocytopenia (decrease of platelets in blood)
Cardiovascular disorder (heart diseases)

male:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Acute respiratory distress syndrome
Thrombocytopenia (decrease of platelets in blood)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Depressed level of consciousness
Diarrhoea
Infection
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
White blood cell count increased

What are the common drug interactions of Zefazone and Pepcid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
C-reactive protein increased
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)

60+:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Leukopenia (less number of white blood cells in blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Depressed level of consciousness
Diarrhoea
Electrolyte imbalance
Hypokalaemia (low potassium)
Infection

* Approximation only. Some reports may have incomplete information.

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