Zelnorm and Prochlorperazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zelnorm (tegaserod maleate) and Prochlorperazine (prochlorperazine). Common drug interactions include abdominal pain among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Zelnorm and Prochlorperazine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

What is Prochlorperazine?

Prochlorperazine has active ingredients of prochlorperazine. It is often used in nausea. eHealthMe is studying from 14,632 Prochlorperazine users. Check the latest studies of Prochlorperazine.



On Jul, 29, 2026

26 people who take Zelnorm and Prochlorperazine together, and have interactions are studied.

Zelnorm and Prochlorperazine drug interactions.

What are the common drug interactions of Zelnorm and Prochlorperazine, by gender? *:

female:

  1. Abdominal pain
  2. Pain
  3. Pain in jaw
  4. Pyrexia (fever)
  5. Actinomycosis (infection that causes sores, or abscesses)
  6. Anaemia (lack of blood)
  7. Angiopathy (generic term for a disease of the blood vessels)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Azotaemia (excess of urea or other nitrogenous compounds in the blood)

male:

  1. Emotional distress

What are the common drug interactions of Zelnorm and Prochlorperazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac disorder
  2. Type 1 diabetes mellitus
  3. Cardiac failure congestive
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Joint injury
  7. Thrombosis (formation of a blood clot inside a blood vessel)
  8. Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

n/a

40-49:

  1. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  2. Polymenorrhoea (menstrual disorder)
  3. Vomiting
  4. Abdominal pain upper
  5. Actinomycosis (infection that causes sores, or abscesses)
  6. Anaemia (lack of blood)
  7. Angiopathy (generic term for a disease of the blood vessels)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

50-59:

  1. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  2. Bacteraemia (presence of bacteria in the blood)
  3. Bone disorder
  4. Bone erosion
  5. Bone fragmentation
  6. Cardiac failure congestive
  7. Congestive cardiomyopathy (weakening of heart muscle)
  8. Constipation
  9. Cough
  10. Deformity (disfigurement)

60+:

  1. Constipation
  2. Small intestinal obstruction (blockage in small intestine)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 57.69%
  2. Multiple Myeloma (cancer of the plasma cells): 14 people, 53.85%
  3. High Blood Pressure: 14 people, 53.85%
  4. Fatigue (feeling of tiredness): 14 people, 53.85%
  5. Irritable Bowel Syndrome: 6 people, 23.08%
  6. Post-Traumatic Stress Disorder: 2 people, 7.69%
  7. Abdominal Pain: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zelnorm and Prochlorperazine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zelnorm and Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zelnorm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zelnorm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prochlorperazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tegaserod maleate and prochlorperazine (the active ingredients of Zelnorm and Prochlorperazine, respectively), and Zelnorm and Prochlorperazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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