Zemplar and Cephalexin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zemplar (paricalcitol) and Cephalexin (cephalexin). Common drug interactions include colonic polyp among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zemplar and Cephalexin. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

What is Cephalexin?

Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.

On Jul, 15, 2026

54 people who take Zemplar and Cephalexin together, and have interactions are studied.

Zemplar and Cephalexin drug interactions.

What are the common drug interactions of Zemplar and Cephalexin, by gender? *:

female:

Colonic polyp (extra part of colon tissue grow in intestine)
Conjunctivitis (pink eye)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery thrombosis (clot formation in coronary artery)
Cough
Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
Deafness
Death
Decreased appetite

male:

Chronic kidney disease
Asthenia (weakness)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Muscle contracture (a permanent shortening of a muscle)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pain in extremity
Pain of skin

What are the common drug interactions of Zemplar and Cephalexin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting

40-49:

Chest discomfort
Chorea (abnormal involuntary movement disorder)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Colonic polyp (extra part of colon tissue grow in intestine)
Confusional state
Conjunctivitis (pink eye)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery thrombosis (clot formation in coronary artery)
Cough

50-59:

Areflexia (absence of a reflex)
Asthenia (weakness)
Contusion (a type of hematoma of tissue in which capillaries)
Dry skin
Erythema (redness of the skin)
Gait disturbance
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Muscle contracture (a permanent shortening of a muscle)

60+:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Coagulopathy (blood's ability to clot is impaired)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Onychomycosis (fungal infection of the nail)
Upper respiratory tract infection
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Renal haemangioma (kidney tumour filled with blood)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 24 people, 44.44%
High Blood Pressure: 21 people, 38.89%
High Blood Cholesterol: 19 people, 35.19%
Pain: 17 people, 31.48%
Diabetes: 11 people, 20.37%
Fluid Retention (an abnormal accumulation of fluid in the blood): 8 people, 14.81%
Insomnia (sleeplessness): 8 people, 14.81%
Nuclear Magnetic Resonance Imaging Abdominal: 7 people, 12.96%
Gout (uric acid crystals building up in the body): 7 people, 12.96%
Neuralgia (pain in one or more nerves): 6 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Zemplar and Cephalexin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously