Zemuron and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zemuron (rocuronium bromide) and Phenergan (promethazine hydrochloride). Common drug interactions include emotional distress among females and necrotising fasciitis among males.

The phase IV clinical study analyzes what interactions people have when they take Zemuron and Phenergan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zemuron?

Zemuron has active ingredients of rocuronium bromide. eHealthMe is studying from 873 Zemuron users. Check the latest studies of Zemuron.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

19 people who take Zemuron and Phenergan together, and have interactions are studied.

Zemuron and Phenergan drug interactions.

What are the common drug interactions of Zemuron and Phenergan, by gender? *:

female:

Emotional distress
Enterococcal infection
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Groin pain
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

male:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nerve injury
Haematemesis (vomiting of blood)
Haemorrhage (bleeding)
Hallucination (an experience involving the perception of something not present)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Scrotal gangrene (death of scrotum cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin ulcer

What are the common drug interactions of Zemuron and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood pressure decreased
Haematemesis (vomiting of blood)
Haemorrhage (bleeding)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Unresponsive to stimuli

30-39:

Abdominal pain
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

Culture urine positive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Delirium (wild excitement)
Diarrhoea
Dyspepsia (indigestion)
Electrocardiogram st-t change
Emotional distress
Enterococcal infection
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Gastroenteritis (inflammation of stomach and intestine)

50-59:

Back pain
Breast mass
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation
Carotid bruit (sound heard over the carotid artery area during auscultation)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colonic polyp (extra part of colon tissue grow in intestine)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dizziness

60+:

Postoperative ileus

What are the existing conditions these people have? *

Pain: 5 people, 26.32%
Depression: 4 people, 21.05%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 15.79%
Migraine Without Aura (headache without neurological problems): 3 people, 15.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
Weight Decreased: 2 people, 10.53%
Type 2 Diabetes: 2 people, 10.53%
Blood Pressure Abnormal: 2 people, 10.53%
Headache (pain in head): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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