Zenpep and Loperamide hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zenpep (pancrelipase (amylase;lipase;protease)) and Loperamide hydrochloride (loperamide hydrochloride). Common drug interactions include abdominal discomfort among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Zenpep and Loperamide hydrochloride. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

On Aug, 11, 2026

16 people who take Zenpep and Loperamide hydrochloride together, and have interactions are studied.

Zenpep and Loperamide hydrochloride drug interactions.

What are the common drug interactions of Zenpep and Loperamide Hydrochloride, by gender? *:

female:

Abdominal discomfort
Anaphylactic reaction (serious allergic reaction)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chills (felling of cold)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness

male:

Abdominal pain
Anaemia (lack of blood)
Glucose urine present
Hepatic enzyme increased
Leukocytosis (increased white blood cells)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Oedema peripheral (superficial swelling)
Platelet count decreased
Pyrexia (fever)
Skin cancer

What are the common drug interactions of Zenpep and Loperamide Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Skin warm
Sneezing
Tenderness (pain or discomfort when an affected area is touched)
Visual impairment
Vomiting
Wheezing (a high-pitched whistling sound made while you breath)
Adverse reaction
Appetite disorder (abnormal eating habits)
Decreased appetite
Intestinal obstruction

60+:

Abdominal discomfort
Anaphylactic reaction (serious allergic reaction)
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Drug hypersensitivity
Dry skin
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphoria (generalized dissatisfaction with life)
Dyspnoea (difficult or laboured respiration)
Ear pain

What are the existing conditions these people have? *

Dizziness: 9 people, 56.25%
Pain: 2 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
High Blood Cholesterol: 2 people, 12.50%
Joint Pain: 2 people, 12.50%
Weight Decreased: 1 person, 6.25%
Inflammation: 1 person, 6.25%
Autoimmune Hepatitis: 1 person, 6.25%
Bipolar Disorder (mood disorder): 1 person, 6.25%
Cystic Fibrosis (disease of the secretary glands): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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