Zenpep and Maxalt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zenpep (pancrelipase (amylase;lipase;protease)) and Maxalt (rizatriptan benzoate). Common drug interactions include blood pressure increased among females and aspartate aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Zenpep and Maxalt. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

11 people who take Zenpep and Maxalt together, and have interactions are studied.

Zenpep and Maxalt drug interactions.

What are the common drug interactions of Zenpep and Maxalt, by gender? *:

female:

  1. Blood pressure increased
  2. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  3. Drug hypersensitivity
  4. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  5. Food allergy
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Headache (pain in head)
  8. Lung infection
  9. Nausea (feeling of having an urge to vomit)
  10. Nephrolithiasis (calculi in the kidneys)

male:

  1. Aspartate aminotransferase increased
  2. Chest discomfort
  3. Weight increased
  4. Diarrhoea
  5. Distal intestinal obstruction syndrome (blockage of the intestines by thickened stool and occurs in individuals with cystic fibrosis)
  6. Gamma-glutamyltransferase increased
  7. Influenza like illness
  8. Nausea (feeling of having an urge to vomit)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Pain

What are the common drug interactions of Zenpep and Maxalt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Gamma-glutamyltransferase increased
  2. Influenza like illness
  3. Nausea (feeling of having an urge to vomit)
  4. Nephrolithiasis (calculi in the kidneys)
  5. Pain
  6. Secretion discharge
  7. Tracheobronchitis (an inflammation or infection, which affects the trachea and bronchi of respiratory tract)
  8. Weight increased
  9. Aspartate aminotransferase increased
  10. Chest discomfort

20-29:

  1. Blood pressure increased
  2. Headache (pain in head)
  3. Vision blurred

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Drug hypersensitivity
  2. Food allergy

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 6 people, 54.55%
  2. Pain: 2 people, 18.18%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 18.18%
  4. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
  5. Fever: 1 person, 9.09%
  6. Constipation: 1 person, 9.09%
  7. Cough: 1 person, 9.09%
  8. Drowsiness: 1 person, 9.09%
  9. Dyspnea (difficult or laboured breathing): 1 person, 9.09%
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zenpep and Maxalt?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zenpep and Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zenpep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zenpep and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and rizatriptan benzoate (the active ingredients of Zenpep and Maxalt, respectively), and Zenpep and Maxalt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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