Zenpep and Trileptal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zenpep (pancrelipase (amylase;lipase;protease)) and Trileptal (oxcarbazepine). Common drug interactions include anaphylactic reaction among females.

The phase IV clinical study analyzes what interactions people have when they take Zenpep and Trileptal. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.



On Jul, 22, 2026

48 people who take Zenpep and Trileptal together, and have interactions are studied.

Zenpep and Trileptal drug interactions.

What are the common drug interactions of Zenpep and Trileptal, by gender? *:

female:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Dysphoria (generalized dissatisfaction with life)
  5. Ear pain
  6. Fatigue (feeling of tiredness)
  7. Gait disturbance
  8. Hallucination (an experience involving the perception of something not present)
  9. Headache (pain in head)
  10. Myalgia (muscle pain)

male:

n/a

What are the common drug interactions of Zenpep and Trileptal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Neck pain
  2. Oedema (fluid collection in tissue)
  3. Oral pain
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Pain
  6. Photophobia (extreme sensitivity to light)
  7. Pruritus (severe itching of the skin)
  8. Rash
  9. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  10. Rhinorrhoea (watery mucus discharge from the nose)

60+:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Diarrhoea
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Dysphoria (generalized dissatisfaction with life)
  7. Ear pain
  8. Fatigue (feeling of tiredness)
  9. Gait disturbance
  10. Haemorrhagic diathesis (bleeding tendency)

What are the existing conditions these people have? *

  1. Dizziness: 42 people, 87.50%
  2. Pain: 14 people, 29.17%

* Approximation only. Some reports may have incomplete information.

Do you take Zenpep and Trileptal?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zenpep and Trileptal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zenpep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trileptal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zenpep and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trileptal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) and oxcarbazepine (the active ingredients of Zenpep and Trileptal, respectively), and Zenpep and Trileptal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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