Zeposia and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zeposia (ozanimod hydrochloride) and Effexor (venlafaxine hydrochloride). Common drug interactions include blood glucose decreased among females.

The phase IV clinical study analyzes what interactions people have when they take Zeposia and Effexor. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zeposia?

Zeposia has active ingredients of ozanimod hydrochloride. eHealthMe is studying from 6,372 Zeposia users. Check the latest studies of Zeposia.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.



On Aug, 12, 2026

12 people who take Zeposia and Effexor together, and have interactions are studied.

Zeposia and Effexor drug interactions.

What are the common drug interactions of Zeposia and Effexor, by gender? *:

female:

  1. Blood glucose decreased
  2. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  3. Weight decreased
  4. Disturbance in attention
  5. Fatigue (feeling of tiredness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Weight increased
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Abdominal discomfort
  10. Abdominal pain

male:

n/a

What are the common drug interactions of Zeposia and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  2. Burning sensation
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Pain
  5. Pruritus (severe itching of the skin)

50-59:

  1. Dizziness
  2. Nausea (feeling of having an urge to vomit)
  3. Osteomyelitis (infection of bone)
  4. Tooth disorder (tooth disease)
  5. Urinary tract infection
  6. Vomiting

60+:

  1. Blood glucose decreased
  2. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pain
  6. Weight decreased
  7. Weight increased
  8. Haemorrhage (bleeding)
  9. Diarrhoea
  10. Laryngitis (inflammation of the larynx)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 41.67%
  2. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
  3. Pain: 3 people, 25.00%
  4. Fatigue (feeling of tiredness): 3 people, 25.00%
  5. Weakness: 2 people, 16.67%
  6. Rickets (softening of bones): 2 people, 16.67%
  7. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 16.67%
  8. Migraine (headache): 2 people, 16.67%
  9. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 16.67%
  10. Headache (pain in head): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zeposia and Effexor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zeposia and Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zeposia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zeposia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ozanimod hydrochloride and venlafaxine hydrochloride (the active ingredients of Zeposia and Effexor, respectively), and Zeposia and Effexor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: