Zerit and Zestril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zerit (stavudine) and Zestril (lisinopril). Common drug interactions include essential hypertension among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Zerit and Zestril. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Zerit?

Zerit has active ingredients of stavudine. eHealthMe is studying from 9,912 Zerit users. Check the latest studies of Zerit.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.

On Jul, 26, 2026

35 people who take Zerit and Zestril together, and have interactions are studied.

What are the common drug interactions of Zerit and Zestril, by gender? *:

female:

Essential hypertension (primary hypertension)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Lactic acidosis (low ph in body tissues)
Multiple fractures
Nausea (feeling of having an urge to vomit)
Pain
Pyelonephritis (inflammation of kidney caused by bacteria)
Rash

male:

Renal failure (kidney dysfunction)
Anxiety
Ataxia (loss of full control of bodily movements)
Dizziness (excl vertigo)
Asthenia (weakness)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fall
Fatigue (feeling of tiredness)
Hepatosplenomegaly (enlargement of both the liver and the spleen)

What are the common drug interactions of Zerit and Zestril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Abdominal pain
Anxiety
Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)
Calcinosis (calcium deposits in any soft tissue)
Cardiac disorder
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

40-49:

Blood lactate dehydrogenase increased
Cholecystitis (infection of gallbladder)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Death
Drooling (drop saliva uncontrollably from the mouth)
Emotional distress
Enzyme abnormality
Fatigue (feeling of tiredness)
Haematemesis (vomiting of blood)
Haemoglobin decreased

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Depression
Renal transplant
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Fatigue (feeling of tiredness)
Fear

60+:

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Failure to thrive (inadequate weight gain and physical growth in children)
Diarrhoea
Fall
General physical health deterioration (weak health status)
Oligodipsia (abnormal absence of thirst)
Parkinson's disease
Blood bicarbonate decreased
Blood carbon dioxide decreased
Blood lactic acid increased

What are the existing conditions these people have? *

Hiv Infection: 10 people, 28.57%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 3 people, 8.57%
Pain: 3 people, 8.57%
Laxative Supportive Care: 3 people, 8.57%
Itching: 3 people, 8.57%
Insomnia (sleeplessness): 3 people, 8.57%
Inflammation: 3 people, 8.57%
Fungal Infection: 3 people, 8.57%
Diarrhea: 3 people, 8.57%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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