Zestoretic and Lamisil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zestoretic (hydrochlorothiazide; lisinopril) and Lamisil (terbinafine hydrochloride). Common drug interactions include chronic kidney disease among females and dermatitis bullous among males.

The phase IV clinical study analyzes what interactions people have when they take Zestoretic and Lamisil. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Zestoretic?

Zestoretic has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 4,342 Zestoretic users. Check the latest studies of Zestoretic.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

On Jul, 07, 2026

22 people who take Zestoretic and Lamisil together, and have interactions are studied.

Zestoretic and Lamisil drug interactions.

What are the common drug interactions of Zestoretic and Lamisil, by gender? *:

female:

Chronic kidney disease
Chest pain
Dyspnoea (difficult or laboured respiration)
Cardiomegaly (increased size of heart than normal)
Hypertensive heart disease
Oedema (fluid collection in tissue)
Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Renal failure (kidney dysfunction)
Abdominal discomfort

male:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Dry throat
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Increased upper airway secretion
Nasopharyngitis (inflammation of the nasopharynx)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vasculitis (inflammation of a blood vessel or blood vessels)

What are the common drug interactions of Zestoretic and Lamisil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cardiomegaly (increased size of heart than normal)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypertensive heart disease
Oedema (fluid collection in tissue)
Dry throat
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Increased upper airway secretion
Palpitations (feelings or sensations that your heart is pounding or racing)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

60+:

Chronic kidney disease
Diarrhoea
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Ataxia (loss of full control of bodily movements)
Back pain
Balance disorder
Blindness unilateral
Bradycardia (abnormally slow heart action)
Breast abscess
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 45.45%
Skin Infection: 5 people, 22.73%
High Blood Cholesterol: 5 people, 22.73%
Fungal Infection: 5 people, 22.73%
Indigestion: 4 people, 18.18%
Constipation: 3 people, 13.64%
Dyspnea (difficult or laboured breathing): 3 people, 13.64%
Pain: 3 people, 13.64%
Gout (uric acid crystals building up in the body): 3 people, 13.64%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Zestoretic and Lamisil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously