Zide and Glucovance drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zide (hydrochlorothiazide) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include lymphoedema among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Zide and Glucovance. It is created by eHealthMe based on reports of 314 people who take the same drugs from the FDA, and is updated regularly.
What is Zide?
Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,231 Zide users. Check the latest studies of Zide.
What is Glucovance?
Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.
314 people who take Zide and Glucovance together, and have interactions are studied.

What are the common drug interactions of Zide and Glucovance, by gender? *
What are the common drug interactions of Zide and Glucovance, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Zide and Glucovance?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zide (183,231 reports)
- Glucovance (6,302 reports)
Browse all drug interactions of Zide and Glucovance:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Zide side effects:
- Zide side effect: Nausea (feeling of having an urge to vomit) (13,185 reports)
- Zide side effect: Dyspnea (difficult or laboured breathing) (10,890 reports)
Browse all side effects of Zide:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Glucovance side effects:
- Glucovance side effect: Blood glucose increased (956 reports)
- Glucovance side effect: Nausea (feeling of having an urge to vomit) (770 reports)
- Glucovance side effect: Weight decreased (531 reports)
- Glucovance side effect: Blood glucose decreased (444 reports)
- Glucovance side effect: Heart attack (365 reports)
Browse all side effects of Glucovance:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Zide interactions:
- Zide and Amlodipine drug interactions: 23,851 reports
- Zide and Aspirin drug interactions: 30,502 reports
- Zide and Atenolol drug interactions: 13,944 reports
- Zide and Lisinopril drug interactions: 28,682 reports
- Zide and Losartan drug interactions: 16,633 reports
- Zide and Metformin drug interactions: 22,445 reports
- Zide and Omeprazole drug interactions: 17,799 reports
- Zide and Prednisone drug interactions: 17,851 reports
- Zide and Simvastatin drug interactions: 15,120 reports
- Zide and Vitamin d drug interactions: 13,199 reports
Browse all interactions between Zide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Glucovance interactions:
- Glucovance and Actos: 729 reports
- Glucovance and Aspirin: 682 reports
- Glucovance and Byetta: 1,216 reports
- Glucovance and Lantus: 587 reports
- Glucovance and Lasix: 504 reports
- Glucovance and Lipitor: 889 reports
- Glucovance and Lisinopril: 468 reports
- Glucovance and Metformin: 520 reports
- Glucovance and Nexium: 401 reports
- Glucovance and Zocor: 413 reports
Browse all interactions between Glucovance and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide and glyburide; metformin hydrochloride (the active ingredients of Zide and Glucovance, respectively), and Zide and Glucovance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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