Zide and Olux drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zide (hydrochlorothiazide) and Olux (clobetasol propionate). Common drug interactions include suicidal ideation among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Zide and Olux. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,246 Zide users. Check the latest studies of Zide.

What is Olux?

Olux has active ingredients of clobetasol propionate. eHealthMe is studying from 614 Olux users. Check the latest studies of Olux.

On Aug, 05, 2026

21 people who take Zide and Olux together, and have interactions are studied.

What are the common drug interactions of Zide and Olux, by gender? *:

female:

Suicidal ideation
Breast cancer
Gait disturbance
Hysterectomy
Nerve injury
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Therapeutic response unexpected
Rash
Neuropathy peripheral (surface nerve damage)
Hyperhidrosis (abnormally increased sweating)

male:

Abscess limb (limb infection)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Psoriasis (immune-mediated disease that affects the skin)
Scab (a hard coating on the skin formed during the wound healing)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Skin disorder (skin disease)
Skin haemorrhage (bleeding into skin)
Abscess bacterial (collection of pus caused by bacteria)
Back pain
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the common drug interactions of Zide and Olux, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus inadequate control
Gait disturbance
Muscular weakness (muscle weakness)
Narcissistic personality disorder (a personality disorder in which the individual is described as being excessively preoccupied with issues of personal)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Psoriasis (immune-mediated disease that affects the skin)
Scab (a hard coating on the skin formed during the wound healing)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Skin disorder (skin disease)

40-49:

n/a

50-59:

n/a

60+:

Breast cancer
Gait disturbance
Injection site papule (solid pimple or swelling at injection site)
Rash
Therapeutic response unexpected
Abscess limb (limb infection)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Enterococcal infection
Klebsiella infection
Abscess bacterial (collection of pus caused by bacteria)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 38.10%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 28.57%
Osteoporosis (bones weak and more likely to break): 3 people, 14.29%
Diabetes: 3 people, 14.29%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 14.29%
Type 2 Diabetes: 2 people, 9.52%
Acrodermatitis (skin condition that typically affects children between the ages of 6 months and 12 years): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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