Zinacef and Cymbalta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zinacef (cefuroxime sodium) and Cymbalta (duloxetine hydrochloride). Common drug interactions include atelectasis among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Zinacef and Cymbalta. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

On Jul, 27, 2026

19 people who take Zinacef and Cymbalta together, and have interactions are studied.

What are the common drug interactions of Zinacef and Cymbalta, by gender? *:

female:

Atelectasis (partial or complete collapse of the lung)
Blood sodium decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
C-reactive protein increased
Cancer pain
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Constipation
Death

male:

Malaise (a feeling of general discomfort or uneasiness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Constipation
Decreased appetite
Device related infection
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress

What are the common drug interactions of Zinacef and Cymbalta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Blood bilirubin increased
Infection

50-59:

Intervertebral disc protrusion (spinal disc protrusion)
Lung neoplasm malignant (cancer tumour of lung)
Lymphatic system neoplasm (tumour of lymphatic system)
Lymphoma (cancer that begins in immune system cells)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Mouth ulceration (mouth ulcers)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Neutropenia (an abnormally low number of neutrophils)

60+:

Blood sodium decreased
C-reactive protein increased
Depressed level of consciousness
Dizziness
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Emotional distress
Fall
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Pain: 7 people, 36.84%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 4 people, 21.05%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 21.05%
Fever: 4 people, 21.05%
Sleep Disorder: 1 person, 5.26%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.26%
Post-Traumatic Stress Disorder: 1 person, 5.26%
Cardiac Disorder: 1 person, 5.26%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.26%
Back Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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