Zinbryta and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zinbryta (daclizumab) and Ibu (ibuprofen). Common drug interactions include drug ineffective among females and multiple sclerosis relapse among males.

The phase IV clinical study analyzes what interactions people have when they take Zinbryta and Ibu. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Zinbryta?

Zinbryta has active ingredients of daclizumab. eHealthMe is studying from 2,382 Zinbryta users. Check the latest studies of Zinbryta.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,532 Ibu users. Check the latest studies of Ibu.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

59 people who take Zinbryta and Ibu together, and have interactions are studied.

What are the common drug interactions of Zinbryta and Ibu, by gender? *:

female:

Drug ineffective
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Decreased appetite
Lymphadenopathy (disease or enlargement of lymph nodes)
Fatigue (feeling of tiredness)
Memory impairment
Herpes virus infection
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Alanine aminotransferase increased
Hydronephrosis (water inside the kidney)
Hypoaesthesia (reduced sense of touch or sensation)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrolithiasis (calculi in the kidneys)
Aspartate aminotransferase increased
Abdominal pain lower
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased

What are the common drug interactions of Zinbryta and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Drug ineffective
Impaired self-care
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Pharyngeal disorder
Abasia (inability to walk)
Feeding disorder (when children refuse to eat certain food groups)
Mobility decreased (ability to move is reduced)

30-39:

Lymphadenopathy (disease or enlargement of lymph nodes)
Herpes virus infection
Drug ineffective
Insomnia (sleeplessness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Ataxia (loss of full control of bodily movements)
Bone marrow disorder
Depression
Fatigue (feeling of tiredness)
Folate deficiency (lack of folic acid)

40-49:

Joint stiffness
Loss of control of legs
Memory impairment
Mobility decreased (ability to move is reduced)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Skin mass
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cystitis (inflammation of the wall of the bladder)
Fall

50-59:

Alopecia (absence of hair from areas of the body)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Decreased appetite
Dermatitis allergic (inflammation of the skin due allergic reaction)
Peripheral swelling
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Drug hypersensitivity
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hypersensitivity

60+:

Asthenia (weakness)
Memory impairment
Flushing (the warm, red condition of human skin)
Hemiparesis (weakness on one side of the body)
Hypotension (abnormally low blood pressure)
Lacrimation increased
Weight increased
Abdominal distension
Fatigue (feeling of tiredness)
Abnormal sensation in eye

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 37 people, 62.71%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 33 people, 55.93%
Headache (pain in head): 12 people, 20.34%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 8 people, 13.56%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 8 people, 13.56%
Herpes Virus Infection: 8 people, 13.56%
Gait Disturbance: 7 people, 11.86%
Depression: 7 people, 11.86%
Fatigue (feeling of tiredness): 6 people, 10.17%
Rickets (softening of bones): 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

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