Ziprasidone hydrochloride and Zolpidem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ziprasidone hydrochloride (ziprasidone hydrochloride) and Zolpidem (zolpidem tartrate). Common drug interactions include drug withdrawal syndrome among females and peripheral vascular disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Ziprasidone hydrochloride and Zolpidem. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Ziprasidone hydrochloride?

Ziprasidone hydrochloride has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 2,001 Ziprasidone hydrochloride users. Check the latest studies of Ziprasidone hydrochloride.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

On Jul, 11, 2026

36 people who take Ziprasidone hydrochloride and Zolpidem together, and have interactions are studied.

Ziprasidone hydrochloride and Zolpidem drug interactions.

What are the common drug interactions of Ziprasidone Hydrochloride and Zolpidem, by gender? *:

female:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hallucination (an experience involving the perception of something not present)
Heart rate increased
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Overdose
Abnormal behaviour
Body temperature increased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure increased

male:

Peripheral vascular disorder
Drug ineffective
Enuresis (repeated inability to control urination)
Salivary hypersecretion (excess saliva secretion)
Suicide attempt
Anxiety
Loss of consciousness
Mood altered (changes in mood)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)

What are the common drug interactions of Ziprasidone Hydrochloride and Zolpidem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood prolactin increased
Depression
Drug ineffective
Electrocardiogram qt prolonged
Galactorrhoea (secretion of breast milk in men)
Lethargy (tiredness)
Suicidal ideation
Weight increased

20-29:

Constipation
Drug ineffective
Enuresis (repeated inability to control urination)
Salivary hypersecretion (excess saliva secretion)
Suicide attempt
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

30-39:

Aggression
Agitation (state of anxiety or nervous excitement)
Drug ineffective
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Psychiatric symptom
Sinus disorder (disease of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hallucination (an experience involving the perception of something not present)
Heart rate increased
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Overdose
Abnormal behaviour
Body temperature increased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure increased

50-59:

Peripheral vascular disorder
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug ineffective
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Psychotic disorder
Therapeutic response decreased (less preventive response)
Visual acuity reduced (reduced clearness of vision)

60+:

Weight increased
Anxiety
Suicidal ideation
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
Adverse drug reaction
Increased appetite
Blood prolactin increased
Depression
Electrocardiogram qt prolonged
Galactorrhoea (secretion of breast milk in men)

What are the existing conditions these people have? *

Hiv Infection: 6 people, 16.67%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 5 people, 13.89%
Bedwetting: 3 people, 8.33%
Stress And Anxiety: 2 people, 5.56%
Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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