Zithromax and Cialis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zithromax (azithromycin) and Cialis (tadalafil). Common drug interactions include physical disability among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Zithromax and Cialis. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.

What is Cialis?

Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.

On Jul, 13, 2026

86 people who take Zithromax and Cialis together, and have interactions are studied.

What are the common drug interactions of Zithromax and Cialis, by gender? *:

female:

Physical disability
Pneumonia
Tardive dyskinesia (a disorder that involves involuntary movements)
Palpitations (feelings or sensations that your heart is pounding or racing)
Ventricular extrasystoles (premature cardiac contraction)
Anxiety
Blood potassium decreased
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Emotional disorder

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Weight increased
Asthenia (weakness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Insomnia (sleeplessness)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal injury (kidney injury)
Bone density decreased
Cardiac failure congestive

What are the common drug interactions of Zithromax and Cialis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Blood potassium decreased
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional disorder
Excessive eye blinking (excessive blinking is dry eyes)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Family stress
Gastritis (inflammation of stomach)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Impaired work ability

30-39:

Acute lung injury
Implant site extravasation
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Weight decreased
Anxiety
Cardiac failure
Death
Drug screen false positive

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Pain
Osteoporosis (bones weak and more likely to break)
Bone loss
Chronic kidney disease
Fracture
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Renal injury (kidney injury)
Weight increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone pain
Depression
Osteopenia (a condition where bone mineral density is lower than normal)
Patella fracture
Upper respiratory tract infection

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Back pain
Cardiac failure congestive
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colonic polyp (extra part of colon tissue grow in intestine)
Cyst (a closed sac)
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 24.42%
Pain: 18 people, 20.93%
High Blood Pressure: 17 people, 19.77%
High Blood Cholesterol: 14 people, 16.28%
Infection: 11 people, 12.79%
Hiv Infection: 10 people, 11.63%
Nausea (feeling of having an urge to vomit): 7 people, 8.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 8.14%
Multiple Myeloma (cancer of the plasma cells): 7 people, 8.14%
Upper Respiratory Tract Infection: 5 people, 5.81%

* Approximation only. Some reports may have incomplete information.

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