Zithromax and Makena drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zithromax (azithromycin) and Makena (hydroxyprogesterone caproate). Common drug interactions include premature delivery among females.

The phase IV clinical study analyzes what interactions people have when they take Zithromax and Makena. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.

What is Makena?

Makena has active ingredients of hydroxyprogesterone caproate. eHealthMe is studying from 24,292 Makena users. Check the latest studies of Makena.

On Jul, 17, 2026

13 people who take Zithromax and Makena together, and have interactions are studied.

What are the common drug interactions of Zithromax and Makena, by gender? *:

female:

Premature delivery
Injection site pain
Limb discomfort (discomfort in leg)
Malaise (a feeling of general discomfort or uneasiness)
Premature labour
Injection site swelling
Amniotic cavity infection
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Ill-defined disorder
Injection site erythema (redness at injection site)

male:

n/a

What are the common drug interactions of Zithromax and Makena, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Injection site pruritus (severe itching at injection site)
Injection site swelling
Injection site urticaria (rash of round, red welts on the skin at injection site)
Malaise (a feeling of general discomfort or uneasiness)
Premature labour
Premature delivery
Ill-defined disorder

30-39:

Injection site pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Injection site erythema (redness at injection site)
Injection site swelling
Limb discomfort (discomfort in leg)
Premature delivery

40-49:

Amniotic cavity infection
Premature delivery

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Premature Delivery: 9 people, 69.23%
Birth Control: 4 people, 30.77%
Nausea (feeling of having an urge to vomit): 3 people, 23.08%
High Blood Pressure: 2 people, 15.38%
Tooth Disorder (tooth disease): 1 person, 7.69%
The Flu (the flu is caused by an influenza virus): 1 person, 7.69%
Infection: 1 person, 7.69%
Indigestion: 1 person, 7.69%
Headache (pain in head): 1 person, 7.69%
Cough: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zithromax and Makena?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously