Zithromax and Maxipime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zithromax (azithromycin) and Maxipime (cefepime hydrochloride). Common drug interactions include dysphonia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Zithromax and Maxipime. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.

What is Maxipime?

Maxipime has active ingredients of cefepime hydrochloride. eHealthMe is studying from 4,279 Maxipime users. Check the latest studies of Maxipime.

On Jul, 25, 2026

68 people who take Zithromax and Maxipime together, and have interactions are studied.

Zithromax and Maxipime drug interactions.

What are the common drug interactions of Zithromax and Maxipime, by gender? *:

female:

Dysphonia (speech disorder attributable to a disorder of phonation)
Haematocrit decreased
Haematoma (collection of blood outside the blood vessels)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Insomnia (sleeplessness)
Leukocytosis (increased white blood cells)
Nausea (feeling of having an urge to vomit)
Pain
Renal failure (kidney dysfunction)
Rhinitis allergic (inflammation of the nasal airways due to allergy)

male:

Pyrexia (fever)
Pneumonia
Decreased appetite
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Night sweats (sweating in night)
Pain
Productive cough
Pruritus (severe itching of the skin)

What are the common drug interactions of Zithromax and Maxipime, by age (0-1 to 60+)? *:

0-1:

Capillary leak syndrome (capillary leaks plasma)
Hypotension (abnormally low blood pressure)

2-9:

n/a

10-19:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Renal failure (kidney dysfunction)
Blood glucose increased
Disturbance in attention
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Septic embolus (a type of embolism that is infected with bacteria)
Skin mass

20-29:

n/a

30-39:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Asthenia (weakness)
Chest pain
Cough
Decreased appetite
Diarrhoea

40-49:

Pyrexia (fever)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Bacteraemia (presence of bacteria in the blood)
Blood calcium increased
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Viral infection
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Alanine aminotransferase increased
Acute tonsillitis

50-59:

Emotional distress
Fear
Genital abscess (build up of pus in genital)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypotension (abnormally low blood pressure)
Injury
Intraductal papillary mucinous neoplasm (tumour (neoplasm) that grows within the pancreatic ducts)
Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
Multi-organ failure (multisystem organ failure)
Obliterative bronchiolitis (bronchiolar inflammation)

60+:

Pneumonia
Febrile neutropenia (fever with reduced white blood cells)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Proctitis (inflammation of the rectum and anus)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac arrest
Cytomegalovirus infection
Delirium (wild excitement)

What are the existing conditions these people have? *

Pain: 13 people, 19.12%
Constipation: 12 people, 17.65%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 11 people, 16.18%
Nausea (feeling of having an urge to vomit): 11 people, 16.18%
Cystic Fibrosis (disease of the secretary glands): 11 people, 16.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 14.71%
Depression: 10 people, 14.71%
Muscle Spasms (muscle contraction): 9 people, 13.24%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 9 people, 13.24%
Rickets (softening of bones): 9 people, 13.24%

* Approximation only. Some reports may have incomplete information.

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