Zocor and Naprelan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zocor (simvastatin) and Naprelan (naproxen sodium). Common drug interactions include injection site reaction among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Zocor and Naprelan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

What is Naprelan?

Naprelan has active ingredients of naproxen sodium. eHealthMe is studying from 731 Naprelan users. Check the latest studies of Naprelan.

On Jul, 08, 2026

18 people who take Zocor and Naprelan together, and have interactions are studied.

What are the common drug interactions of Zocor and Naprelan, by gender? *:

female:

Injection site reaction
Chest pain
Depression
Dry skin
Febrile neutropenia (fever with reduced white blood cells)
Pain in limb
Urticaria (rash of round, red welts on the skin that itch intensely)
Asthenia (weakness)
Crying
Diarrhoea

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Bile duct cancer
Cardiac valve vegetation (heart valve abnormal growth)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic kidney disease
Confusional state
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the common drug interactions of Zocor and Naprelan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Depression
Dry skin
Injection site reaction
Pain in limb
Localised exfoliation (a peeling off or loss of epidermis at the site of exposure)

40-49:

Nausea (feeling of having an urge to vomit)
Hypoaesthesia (reduced sense of touch or sensation)
Myalgia (muscle pain)

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Neuropathy peripheral (surface nerve damage)
Type 2 diabetes mellitus
Diabetic nephropathy (diabetic kidney disease)
Type 1 diabetes mellitus
Acute myocardial infarction (acute heart attack)
Bile duct cancer
Cardiac valve vegetation (heart valve abnormal growth)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Urticaria (rash of round, red welts on the skin that itch intensely)
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Eructation (release of gas from the digestive tract)
Faecal incontinence (a lack of control over passing stool)
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Frequent bowel movements
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)

What are the existing conditions these people have? *

Dyslipidaemia (abnormal amount of lipids): 5 people, 27.78%
Depression: 3 people, 16.67%
Diabetes: 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Headache (pain in head): 3 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 16.67%
Hypersensitivity: 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.11%
Back Pain: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Zocor and Naprelan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously