Zofran and Cancidas drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran (ondansetron hydrochloride) and Cancidas (caspofungin acetate). Common drug interactions include confusional state among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Zofran and Cancidas. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Cancidas?

Cancidas has active ingredients of caspofungin acetate. eHealthMe is studying from 4,879 Cancidas users. Check the latest studies of Cancidas.

On Jul, 29, 2026

85 people who take Zofran and Cancidas together, and have interactions are studied.

What are the common drug interactions of Zofran and Cancidas, by gender? *:

female:

Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dysarthria (speech disorder)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Hemiparesis (weakness on one side of the body)
Hemiplegia (paralysis of one side of the body)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Intracranial haematoma (intracranial localized swelling filled with blood)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

male:

Pyrexia (fever)
Hypotension (abnormally low blood pressure)
Pericardial effusion (fluid around the heart)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain
Fatigue (feeling of tiredness)
Melaena (the passage of black, tarry stools)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Septic shock (shock due to blood infection)
Anaemia (lack of blood)

What are the common drug interactions of Zofran and Cancidas, by age (0-1 to 60+)? *:

0-1:

Abdominal infection
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Ammonia decreased
Anaemia (lack of blood)
Anion gap increased
Aspartate aminotransferase increased
Blast cell count increased
Blood albumin decreased
Blood calcium decreased

2-9:

Epistaxis (bleed from the nose)
Abdominal pain
Depressed level of consciousness
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Agitation (state of anxiety or nervous excitement)
Amaurosis (partial or total blindness without visible change in the eye)
Coma (state of unconsciousness lasting more than six hours)
Fatigue (feeling of tiredness)

10-19:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Haematuria (presence of blood in urine)

20-29:

Pulmonary embolism (blockage of the main artery of the lung)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aphasia (damage to the parts of the brain that control language)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac arrest
Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)

30-39:

Haemoglobin decreased
Pericardial effusion (fluid around the heart)
White blood cell count decreased
Anaemia (lack of blood)
Blood albumin decreased
Blood lactate dehydrogenase increased
Blood urea increased
Bone marrow disorder
Haematocrit decreased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aphasia (damage to the parts of the brain that control language)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac arrest
Confusional state
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

50-59:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Diarrhoea
General physical health deterioration (weak health status)
Hypokalaemia (low potassium)
Hypoxia (low oxygen in tissues)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Cardiomyopathy (weakening of the heart muscle)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Disease progression

60+:

Cardiac failure congestive
Diarrhoea
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Rectal ulcer (ulcer of rectum)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Blood sodium decreased
Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 16.47%
Pain: 11 people, 12.94%
Oesophageal Candidiasis (fungal infection of oesophagus): 7 people, 8.24%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 7 people, 8.24%
Nausea And Vomiting: 6 people, 7.06%
Hiv Infection: 6 people, 7.06%
Abscess (pus): 6 people, 7.06%
Abdominal Discomfort: 6 people, 7.06%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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