Zofran and Micronase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran (ondansetron hydrochloride) and Micronase (glyburide). Common drug interactions include haematoma among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Zofran and Micronase. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Micronase?

Micronase has active ingredients of glyburide. eHealthMe is studying from 1,922 Micronase users. Check the latest studies of Micronase.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

16 people who take Zofran and Micronase together, and have interactions are studied.

Zofran and Micronase drug interactions.

What are the common drug interactions of Zofran and Micronase, by gender? *:

female:

  1. Haematoma (collection of blood outside the blood vessels)
  2. Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
  3. Neoplasm malignant (cancer tumour)
  4. Overdose
  5. Renal disorder (kidney disease)
  6. Road traffic accident
  7. Tooth loss
  8. Anxiety
  9. Injury
  10. Pain

male:

  1. Pleural effusion (water on the lungs)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Cardiomegaly (increased size of heart than normal)
  7. Flatulence (flatus expelled through the anus)
  8. Hydronephrosis (water inside the kidney)
  9. Hyperthyroidism (over activity of the thyroid gland)
  10. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the common drug interactions of Zofran and Micronase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
  2. Pain
  3. Anxiety
  4. Emotional distress
  5. General physical condition
  6. General physical health deterioration (weak health status)
  7. Injury

40-49:

n/a

50-59:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Pleural effusion (water on the lungs)

60+:

  1. Swelling face
  2. Anaemia (lack of blood)
  3. Eye infection viral
  4. Fall
  5. Gallbladder enlargement
  6. Gingival erosion (gum ulcer)
  7. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the existing conditions these people have? *

  1. Bone Density Decreased: 5 people, 31.25%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 12.50%
  3. Pain: 2 people, 12.50%
  4. Infection: 2 people, 12.50%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  6. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1 person, 6.25%
  7. Headache (pain in head): 1 person, 6.25%
  8. Birth Control: 1 person, 6.25%
  9. Bone Loss: 1 person, 6.25%
  10. Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and Micronase?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zofran and Micronase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Micronase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zofran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Micronase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride and glyburide (the active ingredients of Zofran and Micronase, respectively), and Zofran and Micronase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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