Zofran and Turalio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zofran (ondansetron hydrochloride) and Turalio (pexidartinib hydrochloride). Common drug interactions include arthritis among females and adverse event among males.

The phase IV clinical study analyzes what interactions people have when they take Zofran and Turalio. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Turalio?

Turalio has active ingredients of pexidartinib hydrochloride. eHealthMe is studying from 1,355 Turalio users. Check the latest studies of Turalio.



On Jul, 11, 2026

18 people who take Zofran and Turalio together, and have interactions are studied.

Zofran and Turalio drug interactions.

What are the common drug interactions of Zofran and Turalio, by gender? *:

female:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Blood albumin increased
  3. Blood calcium increased
  4. Hot flush (sudden feelings of heat)
  5. Hypersensitivity
  6. Mean cell volume increased (more than normal average red blood cell volume)
  7. Myalgia (muscle pain)
  8. Pain in extremity
  9. Tenderness (pain or discomfort when an affected area is touched)
  10. Tooth disorder (tooth disease)

male:

  1. Adverse event
  2. Hepatic enzyme increased

What are the common drug interactions of Zofran and Turalio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Hair colour changes
  3. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  4. Abdominal discomfort
  5. Constipation
  6. Blood albumin increased
  7. Blood calcium increased
  8. Dysgeusia (disorder of the sense of taste)
  9. Eye swelling
  10. Adverse event

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Giant Cell Tumor Of Tendon Sheath: 12 people, 66.67%
  2. Synovitis (inflammation of the synovial membrane): 11 people, 61.11%
  3. Pain: 7 people, 38.89%
  4. Stress And Anxiety: 5 people, 27.78%
  5. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 16.67%
  6. Itching: 2 people, 11.11%
  7. Face Oedema (swelling of face): 2 people, 11.11%
  8. Diarrhea: 2 people, 11.11%
  9. Depression: 2 people, 11.11%
  10. Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and Turalio?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zofran and Turalio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Turalio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zofran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Turalio and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride and pexidartinib hydrochloride (the active ingredients of Zofran and Turalio, respectively), and Zofran and Turalio (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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