Zoladex and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoladex (goserelin acetate) and Morphine sulfate (morphine sulfate). Common drug interactions include anxiety among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Zoladex and Morphine sulfate. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Zoladex?

Zoladex has active ingredients of goserelin acetate. It is often used in prostate cancer. eHealthMe is studying from 13,870 Zoladex users. Check the latest studies of Zoladex.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

73 people who take Zoladex and Morphine sulfate together, and have interactions are studied.

Zoladex and Morphine sulfate drug interactions.

What are the common drug interactions of Zoladex and Morphine Sulfate, by gender? *:

female:

Anxiety
Pain in extremity
Fall
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Metastases to bone (cancer spreads to bone)
Osteonecrosis of jaw (death of bone of jaw)
General physical health deterioration (weak health status)
Dyspnoea (difficult or laboured respiration)
Intervertebral disc degeneration (spinal disc degeneration)
Ligament sprain (ligament stretched)

male:

Anxiety
Dyspnoea (difficult or laboured respiration)
Constipation
Hypotension (abnormally low blood pressure)
Injury
Intervertebral disc protrusion (spinal disc protrusion)
Spinal osteoarthritis (joint cartilage loss in spine)
Chest pain
Dizziness
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the common drug interactions of Zoladex and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

General physical health deterioration (weak health status)
Hepatic neoplasm malignant (liver cancer)
Hepatomegaly (abnormal enlargement of the liver)
Neoplasm malignant (cancer tumour)
Neoplasm progression (growth of tumour)
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Peristalsis visible (visible wavelike muscular contractions of the alimentary canal or other tubular structures)
Tumour marker increased
Blood potassium decreased
Death

40-49:

Anxiety
Depression
Weight decreased
Diarrhoea
Fall
Metastases to bone (cancer spreads to bone)
Abdominal discomfort
Constipation
Chest pain
Hypotension (abnormally low blood pressure)

50-59:

Dyspnoea (difficult or laboured respiration)
Erythrodermic psoriasis (generalized redness of the skin)
Exercise tolerance decreased
Gamma-glutamyltransferase increased
Haemoglobin decreased
Mean cell volume increased (more than normal average red blood cell volume)
C-reactive protein increased
Device related infection
Eosinophil count decreased
Mucosal inflammation (infection of mucous membrane)

60+:

Anaemia (lack of blood)
Anxiety
Septic shock (shock due to blood infection)
Bone pain
Dyspnoea (difficult or laboured respiration)
Pneumonia
Arrhythmia (irregular heartbeat)
Bone disorder
Bone loss
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 7 people, 9.59%
Breast Cancer Metastatic: 7 people, 9.59%
Nausea (feeling of having an urge to vomit): 5 people, 6.85%
Breast Cancer: 5 people, 6.85%
Prostate Cancer Metastatic: 4 people, 5.48%
High Blood Pressure: 4 people, 5.48%
Constipation: 4 people, 5.48%
Bone Pain: 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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