Zoladex and Nexavar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoladex (goserelin acetate) and Nexavar (sorafenib tosylate). Common drug interactions include cerebral infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Zoladex and Nexavar. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zoladex?

Zoladex has active ingredients of goserelin acetate. It is often used in prostate cancer. eHealthMe is studying from 13,870 Zoladex users. Check the latest studies of Zoladex.

What is Nexavar?

Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 23,250 Nexavar users. Check the latest studies of Nexavar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

12 people who take Zoladex and Nexavar together, and have interactions are studied.

What are the common drug interactions of Zoladex and Nexavar, by gender? *:

female:

n/a

male:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Angioedema (rapid swelling of the dermis)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Dysuria (painful or difficult urination)
Malignant neoplasm progression (cancer tumour came back)
Hepatic neoplasm malignant (liver cancer)
Rash

What are the common drug interactions of Zoladex and Nexavar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Angioedema (rapid swelling of the dermis)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Dysuria (painful or difficult urination)
Malignant neoplasm progression (cancer tumour came back)
Hepatic neoplasm malignant (liver cancer)
Rash

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 41.67%
Renal Cell Carcinoma (a kidney cancer): 4 people, 33.33%
Productive Cough: 4 people, 33.33%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 33.33%
Hepatitis B: 4 people, 33.33%
Hepatitis (inflammation of the liver): 4 people, 33.33%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 33.33%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 3 people, 25.00%
Pancreatitis (inflammation of pancreas): 2 people, 16.67%
Liver Disorder (liver diseases): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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