Zoledronic acid and Plendil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zoledronic acid (zoledronic acid) and Plendil (felodipine). Common drug interactions include juvenile idiopathic arthritis among females and carotid artery stenosis among males.
The phase IV clinical study analyzes what interactions people have when they take Zoledronic acid and Plendil. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Zoledronic acid?
Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.
What is Plendil?
Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.
12 people who take Zoledronic acid and Plendil together, and have interactions are studied.

What are the common drug interactions of Zoledronic Acid and Plendil, by gender? *:
female:
- Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
- Peripheral swelling
- Swelling
- Ageusia (loss of taste functions of the tongue)
- Vision blurred
male:
- Carotid artery stenosis (narrowing of carotid artery)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Lacunar infarction (a type of stroke)
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- International normalised ratio decreased
- Metastases to bone (cancer spreads to bone)
- Metastases to spine (cancer spreads to spine)
- Prostate cancer
- Carotid artery dissection
What are the common drug interactions of Zoledronic Acid and Plendil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Juvenile idiopathic arthritis (a subset of arthritis seen in childhood)
- Peripheral swelling
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Lacunar infarction (a type of stroke)
- Metastases to bone (cancer spreads to bone)
- Metastases to spine (cancer spreads to spine)
- Prostate cancer
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Vision blurred
- Swelling
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 6 people, 50.00%
- Prostate Cancer Metastatic: 2 people, 16.67%
- Nausea (feeling of having an urge to vomit): 1 person, 8.33%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
- Joint Pain: 1 person, 8.33%
- Insomnia (sleeplessness): 1 person, 8.33%
- Indigestion: 1 person, 8.33%
- Eye Disorder: 1 person, 8.33%
- Constipation: 1 person, 8.33%
- Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Zoledronic acid and Plendil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zoledronic acid (28,485 reports)
- Plendil (4,990 reports)
Browse all drug interactions of Zoledronic acid and Plendil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zoledronic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Plendil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoledronic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Plendil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and felodipine (the active ingredients of Zoledronic acid and Plendil, respectively), and Zoledronic acid and Plendil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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