Zoledronic and Embolex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Embolex (dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride). Common drug interactions include necrosis among females and malignant neoplasm progression among males.

The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Embolex. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Embolex?

Embolex has active ingredients of dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride. eHealthMe is studying from 1,161 Embolex users. Check the latest studies of Embolex.



On Jul, 20, 2026

11 people who take Zoledronic and Embolex together, and have interactions are studied.

Zoledronic and Embolex drug interactions.

What are the common drug interactions of Zoledronic and Embolex, by gender? *:

female:

  1. Necrosis (the death of body tissue)
  2. Subcutaneous abscess
  3. Asthenia (weakness)
  4. Diarrhoea
  5. Hair colour changes
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Metastatic renal cell carcinoma (spreadable kidney cell tumour)
  8. Pain in extremity
  9. Pneumonia

male:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Metastases to spine (cancer spreads to spine)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Metastatic malignant melanoma (spreadable cancer tumour of melanine)
  5. Spinal fracture (fracture in one of vertebrae)
  6. Cholecystitis (infection of gallbladder)
  7. Hepatitis (inflammation of the liver)
  8. Metastases to meninges (cancer spreads to meninges)
  9. Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)
  10. Oesophageal candidiasis (fungal infection of oesophagus)

What are the common drug interactions of Zoledronic and Embolex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diarrhoea
  2. Hair colour changes
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Metastatic renal cell carcinoma (spreadable kidney cell tumour)
  5. Pain in extremity
  6. Pneumonia
  7. Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)
  8. Pathological fracture (broken bone caused by disease)
  9. Asthenia (weakness)

60+:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Metastases to spine (cancer spreads to spine)
  3. Metastatic malignant melanoma (spreadable cancer tumour of melanine)
  4. Spinal fracture (fracture in one of vertebrae)
  5. Cholecystitis (infection of gallbladder)
  6. Hepatitis (inflammation of the liver)
  7. Metastases to meninges (cancer spreads to meninges)
  8. Oesophageal candidiasis (fungal infection of oesophagus)
  9. Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

  1. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 4 people, 36.36%
  2. Malignant Melanoma (skin cancer rises from melancytes): 4 people, 36.36%
  3. High Blood Pressure: 3 people, 27.27%
  4. Breast Cancer: 3 people, 27.27%
  5. Pain: 3 people, 27.27%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 18.18%
  7. Osteolysis (dissolution of bone): 2 people, 18.18%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 18.18%
  9. Neuralgia (pain in one or more nerves): 1 person, 9.09%
  10. Nausea (feeling of having an urge to vomit): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and Embolex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zoledronic and Embolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Embolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Embolex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid and dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride (the active ingredients of Zoledronic and Embolex, respectively), and Zoledronic and Embolex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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