Zoledronic and Ms contin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zoledronic (zoledronic acid) and Ms contin (morphine sulfate). Common drug interactions include atrial fibrillation among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Zoledronic and Ms contin. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.
What is Zoledronic?
Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.
What is Ms contin?
Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.
68 people who take Zoledronic and Ms contin together, and have interactions are studied.

What are the common drug interactions of Zoledronic and Ms Contin, by gender? *:
female:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac arrest
- Cardiac failure
- Constipation
- Death
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Mobility decreased (ability to move is reduced)
- Mucosal inflammation (infection of mucous membrane)
- Muscular weakness (muscle weakness)
male:
- Anaemia (lack of blood)
- Vomiting
- Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
- Oxygen saturation decreased
- Productive cough
- Renal failure (kidney dysfunction)
- Blood glucose increased
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Abdominal distension
- Arrhythmia (irregular heartbeat)
What are the common drug interactions of Zoledronic and Ms Contin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Hypersensitivity
- Blood creatinine increased
- Dizziness
- Headache (pain in head)
- Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
- Proteinuria (presence of protein in the urine)
- Pruritus (severe itching of the skin)
- Rash
- Renal impairment (severely reduced kidney function)
- Viral infection
10-19:
n/a
20-29:
n/a
30-39:
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
- Eye swelling
- Pupils unequal
- Vision blurred
- Visual acuity reduced (reduced clearness of vision)
40-49:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Drug ineffective
- Fatigue (feeling of tiredness)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Somnolence (a state of near-sleep, a strong desire for sleep)
50-59:
- Renal injury (kidney injury)
- Septic shock (shock due to blood infection)
- Vomiting
- Bone marrow failure
- Breast cancer recurrent
- Carcinoembryonic antigen increased
- Cardiotoxicity (damage to the heart muscle)
- Metastases to bone (cancer spreads to bone)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Neoplasm malignant (cancer tumour)
60+:
- Neutropenia (an abnormally low number of neutrophils)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Constipation
- Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
- Nausea (feeling of having an urge to vomit)
- Oxygen saturation decreased
- Productive cough
- Renal failure (kidney dysfunction)
- Vomiting
- Blood glucose increased
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 32 people, 47.06%
- Metastases To Bone (cancer spreads to bone): 12 people, 17.65%
- Nausea (feeling of having an urge to vomit): 10 people, 14.71%
- Prostate Cancer Metastatic: 8 people, 11.76%
- Prostate Cancer: 7 people, 10.29%
- Cough: 5 people, 7.35%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 5.88%
- High Blood Pressure: 4 people, 5.88%
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 5.88%
- Allergic Rhinitis: 4 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Zoledronic and Ms contin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zoledronic (29,812 reports)
- Ms contin (69,289 reports)
Browse all drug interactions of Zoledronic and Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ms contin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoledronic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ms contin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and morphine sulfate (the active ingredients of Zoledronic and Ms contin, respectively), and Zoledronic and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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