Zolmitriptan and Botox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolmitriptan (zolmitriptan) and Botox (botulinum toxin type a). Common drug interactions include headache among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Zolmitriptan and Botox. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Zolmitriptan?

Zolmitriptan has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 2,568 Zolmitriptan users. Check the latest studies of Zolmitriptan.

What is Botox?

Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.

On Jul, 29, 2026

67 people who take Zolmitriptan and Botox together, and have interactions are studied.

Zolmitriptan and Botox drug interactions.

What are the common drug interactions of Zolmitriptan and Botox, by gender? *:

female:

Headache (pain in head)
Asthenia (weakness)
Muscular weakness (muscle weakness)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Vomiting
Blood pressure increased
Alanine aminotransferase increased
Blood cholesterol increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Drug ineffective
Affect lability (emotional incontinence)
Vision blurred
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Death
Gait disturbance
Headache (pain in head)
Pruritus (severe itching of the skin)
Sinusitis (inflammation of sinus)
Skin haemorrhage (bleeding into skin)

What are the common drug interactions of Zolmitriptan and Botox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)

30-39:

Swelling face
Muscular weakness (muscle weakness)
Dysarthria (speech disorder)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Lid lag (immobility or lagging of the upper eyelid on downward rotation of the eye)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Death

40-49:

Dry eye (lack of adequate tears)
Eye pruritus (eye itching)
Injection site reaction
Lip swelling
Oral candidiasis (fungal infection of mouth)
Oral mucosal erythema (redness of the mucous membrane of mouth)
Skin lesion
Drug ineffective
Pain
Abdominal discomfort

50-59:

Alanine aminotransferase increased
Asthenia (weakness)
Blood cholesterol increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Fatigue (feeling of tiredness)
Gamma-glutamyltransferase increased
General physical health deterioration (weak health status)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Asthenia (weakness)
Blood pressure increased
Sinusitis (inflammation of sinus)
Skin haemorrhage (bleeding into skin)
Vision blurred
Headache (pain in head)
Migraine without aura (headache without neurological problems)
Affect lability (emotional incontinence)
Asthma
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 17.91%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 13.43%
Sunct Syndrome (short lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing): 7 people, 10.45%
Headache (pain in head): 6 people, 8.96%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 5 people, 7.46%
Nausea (feeling of having an urge to vomit): 4 people, 5.97%
Eosinophilic Esophagitis (Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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