Zolpidem and Amphetamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Amphetamine (amphetamine). Common drug interactions include tendonitis among females and overdose among males.
The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Amphetamine. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Zolpidem?
Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.
What is Amphetamine?
Amphetamine has active ingredients of amphetamine. eHealthMe is studying from 980 Amphetamine users. Check the latest studies of Amphetamine.
48 people who take Zolpidem and Amphetamine together, and have interactions are studied.

What are the common drug interactions of Zolpidem and Amphetamine, by gender? *:
female:
- Tendonitis (a condition that causes pain and swelling of tendons)
- Tinnitus (a ringing in the ears)
- Vision blurred
- Vitamin d decreased
- Wound
- Abdominal pain
- Chronic kidney disease
- Colitis (inflammation of colon)
- Deafness
- Eye swelling
male:
- Overdose
- Drug abuse
- Nephrolithiasis (calculi in the kidneys)
- Mobility decreased (ability to move is reduced)
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Hypertension (high blood pressure)
- Impetigo (contagious skin infection)
- Neuromuscular blockade
- Pruritus (severe itching of the skin)
What are the common drug interactions of Zolpidem and Amphetamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Overdose
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Drug abuse
- Death
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Cardiac arrest
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Impetigo (contagious skin infection)
- Neuromuscular blockade
40-49:
- Back pain
- Drug abuse
- Injection site abscess
- Intervertebral discitis (infection in the intervertebral disc space)
- Arthralgia (joint pain)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
50-59:
- Fall
- Mobility decreased (ability to move is reduced)
- Chronic kidney disease
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Eye swelling
- Foot fracture
- Gait disturbance
- Hypersensitivity
- Muscular weakness (muscle weakness)
- Nephrogenic anaemia (anaemia due to kidney disease)
60+:
- Loss of consciousness
- Malaise (a feeling of general discomfort or uneasiness)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Back pain
- Breast disorder
- Breast mass
- Cardiac disorder
- Crying
- Depression
What are the existing conditions these people have? *
- Drug Abuse: 4 people, 8.33%
- Pain: 3 people, 6.25%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.25%
- Drowsiness: 3 people, 6.25%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Zolpidem and Amphetamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zolpidem (92,695 reports)
- Amphetamine (980 reports)
Browse all drug interactions of Zolpidem and Amphetamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amphetamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zolpidem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amphetamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on zolpidem tartrate and amphetamine (the active ingredients of Zolpidem and Amphetamine, respectively), and Zolpidem and Amphetamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Gastrointestinal Tract Adenoma and drugs of ingredients of metformin hydrochloride - now
- Could Tobradex cause Metastases To Bone? - 6 seconds ago
- Vitamin B6 and High Blood Pressure for Men aged 50-59 - 10 seconds ago
- Vitamin B6 and Htn for Men aged 50-59 - 10 seconds ago
- Vitamin B6 and Hypertension for Men aged 50-59 - 11 seconds ago
- Vitamin B6 and Hbp for Men aged 50-59 - 11 seconds ago
- Vitamin B6 and Blood Pressure - High for Men aged 50-59 - 11 seconds ago
- Vitamin B6 and Blood Pressure Increased for Men aged 50-59 - 12 seconds ago
- Could Citalopram Hydrobromide cause Cerebellar Syndrome? - 14 seconds ago
- Adderall 20 vs. Inositol, side effect and effectiveness comparison - 18 seconds ago