Zolpidem and Amphetamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Amphetamine (amphetamine). Common drug interactions include tendonitis among females and overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Amphetamine. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Amphetamine?

Amphetamine has active ingredients of amphetamine. eHealthMe is studying from 980 Amphetamine users. Check the latest studies of Amphetamine.



On Aug, 09, 2026

48 people who take Zolpidem and Amphetamine together, and have interactions are studied.

Zolpidem and Amphetamine drug interactions.

What are the common drug interactions of Zolpidem and Amphetamine, by gender? *:

female:

  1. Tendonitis (a condition that causes pain and swelling of tendons)
  2. Tinnitus (a ringing in the ears)
  3. Vision blurred
  4. Vitamin d decreased
  5. Wound
  6. Abdominal pain
  7. Chronic kidney disease
  8. Colitis (inflammation of colon)
  9. Deafness
  10. Eye swelling

male:

  1. Overdose
  2. Drug abuse
  3. Nephrolithiasis (calculi in the kidneys)
  4. Mobility decreased (ability to move is reduced)
  5. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Hypertension (high blood pressure)
  8. Impetigo (contagious skin infection)
  9. Neuromuscular blockade
  10. Pruritus (severe itching of the skin)

What are the common drug interactions of Zolpidem and Amphetamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Overdose
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Drug abuse
  4. Death
  5. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  6. Cardiac arrest
  7. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  9. Impetigo (contagious skin infection)
  10. Neuromuscular blockade

40-49:

  1. Back pain
  2. Drug abuse
  3. Injection site abscess
  4. Intervertebral discitis (infection in the intervertebral disc space)
  5. Arthralgia (joint pain)
  6. Headache (pain in head)
  7. Nausea (feeling of having an urge to vomit)

50-59:

  1. Fall
  2. Mobility decreased (ability to move is reduced)
  3. Chronic kidney disease
  4. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  5. Eye swelling
  6. Foot fracture
  7. Gait disturbance
  8. Hypersensitivity
  9. Muscular weakness (muscle weakness)
  10. Nephrogenic anaemia (anaemia due to kidney disease)

60+:

  1. Loss of consciousness
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Back pain
  6. Breast disorder
  7. Breast mass
  8. Cardiac disorder
  9. Crying
  10. Depression

What are the existing conditions these people have? *

  1. Drug Abuse: 4 people, 8.33%
  2. Pain: 3 people, 6.25%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 6.25%
  4. Drowsiness: 3 people, 6.25%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zolpidem and Amphetamine:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amphetamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zolpidem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amphetamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate and amphetamine (the active ingredients of Zolpidem and Amphetamine, respectively), and Zolpidem and Amphetamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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