Zolpidem and Droxidopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Droxidopa (droxidopa). Common drug interactions include dyskinesia among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Droxidopa. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Droxidopa?

Droxidopa has active ingredients of droxidopa. eHealthMe is studying from 1,093 Droxidopa users. Check the latest studies of Droxidopa.

On Aug, 12, 2026

17 people who take Zolpidem and Droxidopa together, and have interactions are studied.

Zolpidem and Droxidopa drug interactions.

What are the common drug interactions of Zolpidem and Droxidopa, by gender? *:

female:

Dyskinesia (abnormality or impairment of voluntary movement)
Fall
Fractured sacrum
Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Osteoporosis (bones weak and more likely to break)
Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Loss of consciousness
Acidosis (build-up of carbon dioxide in the blood)

male:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Amnestic disorder (group of disorders that involve loss of memories previously established, loss of the ability to create new memories)
Presyncope
Pyrexia (fever)
Road traffic accident
Vocal cord paralysis
Vomiting
Cardiac arrest
Fall
Haemoglobin increased

What are the common drug interactions of Zolpidem and Droxidopa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acidosis (build-up of carbon dioxide in the blood)
Depressed level of consciousness
Electrocardiogram qrs complex prolonged
Electrolyte imbalance
Hyperreflexia (overactive or over responsive reflexes)
Hyperthermia (body temperature greatly above normal)
Hypotension (abnormally low blood pressure)
Muscle rigidity (muscle stiffness)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Nervous system disorder (a general class of medical conditions affecting the nervous system)

50-59:

Dyskinesia (abnormality or impairment of voluntary movement)
Fall
Fractured sacrum
Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Osteoporosis (bones weak and more likely to break)

60+:

Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Nerve block (the interruption of signals travelling along a nerve)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pneumonia
Postresuscitation encephalopathy
Presyncope
Pyrexia (fever)
Road traffic accident
Vocal cord paralysis

What are the existing conditions these people have? *

Nausea And Vomiting: 5 people, 29.41%
Nausea (feeling of having an urge to vomit): 5 people, 29.41%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 5 people, 29.41%
Abdominal Distension: 5 people, 29.41%
Parkinson's Disease: 2 people, 11.76%
Hiv Infection: 2 people, 11.76%
Cardiac Amyloidosis (protein deposition in heart): 2 people, 11.76%
Osteoporosis (bones weak and more likely to break): 1 person, 5.88%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.88%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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