Zolpidem and Feldene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Feldene (piroxicam). Common drug interactions include fall among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Feldene. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

29 people who take Zolpidem and Feldene together, and have interactions are studied.

What are the common drug interactions of Zolpidem and Feldene, by gender? *:

female:

Fall
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Nausea (feeling of having an urge to vomit)
Vomiting
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebral atrophy (decrement in size of brain)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)

male:

Chest pain
Pulmonary embolism (blockage of the main artery of the lung)
Blood bilirubin increased
Erythema multiforme (a type of hypersensitivity reaction)
Lung disorder (lung disease)

What are the common drug interactions of Zolpidem and Feldene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Haemorrhage intracranial (bleeding within the skull)

50-59:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Neuropathy peripheral (surface nerve damage)
Pruritus (severe itching of the skin)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
Blood bilirubin increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

60+:

Confusional state
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Pain: 11 people, 37.93%
Depression: 8 people, 27.59%
Nausea (feeling of having an urge to vomit): 5 people, 17.24%
Fever: 4 people, 13.79%
High Blood Pressure: 4 people, 13.79%
Body Temperature Increased: 4 people, 13.79%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 13.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.79%
Headache (pain in head): 4 people, 13.79%
Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 4 people, 13.79%

* Approximation only. Some reports may have incomplete information.

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