Zometa and Bydureon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zometa (zoledronic acid) and Bydureon (exenatide synthetic). Common drug interactions include abnormal weight gain among females and osteonecrosis of jaw among males.

The phase IV clinical study analyzes what interactions people have when they take Zometa and Bydureon. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

What is Bydureon?

Bydureon has active ingredients of exenatide synthetic. It is often used in type 2 diabetes. eHealthMe is studying from 24,309 Bydureon users. Check the latest studies of Bydureon.

On Aug, 05, 2026

11 people who take Zometa and Bydureon together, and have interactions are studied.

What are the common drug interactions of Zometa and Bydureon, by gender? *:

female:

Abnormal weight gain
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Arthralgia (joint pain)
Bedridden
Bladder disorder
Blood potassium decreased
Constipation
Decreased appetite
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)

male:

Osteonecrosis of jaw (death of bone of jaw)
Exposed bone in jaw
Ankle fracture
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Coagulopathy (blood's ability to clot is impaired)
Fall
Foot fracture
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Renal failure (kidney dysfunction)

What are the common drug interactions of Zometa and Bydureon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Osteonecrosis of jaw (death of bone of jaw)
Exposed bone in jaw
Constipation
Decreased appetite
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Fatigue (feeling of tiredness)
Foot fracture
Hypotension (abnormally low blood pressure)
Lower respiratory tract infection

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 3 people, 27.27%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 1 person, 9.09%
Oedema (fluid collection in tissue): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
Heart Rate Irregular: 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Diabetes: 1 person, 9.09%
Cancer Pain: 1 person, 9.09%
Breast Cancer Metastatic: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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