Zometa and Pentacarinat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zometa (zoledronic acid) and Pentacarinat (pentamidine isethionate). Common drug interactions include neutropenia among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Zometa and Pentacarinat. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

What is Pentacarinat?

Pentacarinat has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,546 Pentacarinat users. Check the latest studies of Pentacarinat.



On Jul, 08, 2026

41 people who take Zometa and Pentacarinat together, and have interactions are studied.

Zometa and Pentacarinat drug interactions.

What are the common drug interactions of Zometa and Pentacarinat, by gender? *:

female:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Anaemia (lack of blood)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
  6. Asthenia (weakness)
  7. Back pain
  8. Gingivitis (inflammation of gums)
  9. Infusion related reaction
  10. Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

male:

  1. Loss of consciousness
  2. Diarrhoea
  3. Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
  4. Gastrointestinal perforation (hole in the digestive tract)
  5. Confusional state
  6. Delusion (a false belief or opinion)
  7. Dental caries
  8. Exposed bone in jaw
  9. General physical health deterioration (weak health status)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Zometa and Pentacarinat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Dental caries
  2. Exposed bone in jaw
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Pain in jaw

60+:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Loss of consciousness
  3. Anaemia (lack of blood)
  4. Colitis (inflammation of colon)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
  7. Asthenia (weakness)
  8. Back pain
  9. Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
  10. Gastrointestinal perforation (hole in the digestive tract)

What are the existing conditions these people have? *

  1. High Blood Pressure: 13 people, 31.71%
  2. Constipation: 9 people, 21.95%
  3. Hypercalcaemia (elevated calcium (ca+) level in the blood): 8 people, 19.51%
  4. Hyperglycemia (high blood sugar): 8 people, 19.51%
  5. Lymphoma (cancer that begins in immune system cells): 6 people, 14.63%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 14.63%
  7. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 6 people, 14.63%
  8. Insomnia (sleeplessness): 6 people, 14.63%
  9. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 14.63%
  10. Osteoporosis (bones weak and more likely to break): 6 people, 14.63%

* Approximation only. Some reports may have incomplete information.

Do you take Zometa and Pentacarinat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zometa and Pentacarinat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zometa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pentacarinat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zometa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentacarinat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid and pentamidine isethionate (the active ingredients of Zometa and Pentacarinat, respectively), and Zometa and Pentacarinat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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