Zonisamide and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Azithromycin (azithromycin). Common drug interactions include urinary tract infection among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Azithromycin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

On Jul, 05, 2026

36 people who take Zonisamide and Azithromycin together, and have interactions are studied.

Zonisamide and Azithromycin drug interactions.

What are the common drug interactions of Zonisamide and Azithromycin, by gender? *:

female:

Urinary tract infection
Pain
Chronic kidney disease
Fatigue (feeling of tiredness)
Diarrhoea
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Pneumonia
Alopecia (absence of hair from areas of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspnoea (difficult or laboured respiration)
Weight increased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Face injury
Fall
Bacterial infection
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pneumonia

What are the common drug interactions of Zonisamide and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Respiratory disorder (respiratory disease)

10-19:

Priapism (prolonged and painful erection that can last from several hours up to a few days)
Drug ineffective

20-29:

Diarrhoea
Abdominal discomfort
Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholesterosis (abnormal deposition of cholesterol in tissues)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Faeces discoloured
Hypokalaemia (low potassium)

30-39:

Pain
Pulmonary embolism (blockage of the main artery of the lung)
Acidosis (build-up of carbon dioxide in the blood)
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Delayed recovery from anaesthesia
Dyspnoea (difficult or laboured respiration)
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

40-49:

Asthma
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Heart rate irregular
Influenza
Pneumonia
Pyrexia (fever)
Upper airway obstruction
Upper respiratory tract infection

50-59:

Pain
Chronic kidney disease
Alopecia (absence of hair from areas of the body)
Drug ineffective
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Ill-defined disorder
Infusion site erythema (reddening of the skin at infusion site)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Face injury
Fall
Bacterial infection
Chronic kidney disease
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Muscle spasms (muscle contraction)
Mycobacterium avium complex infection

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
Stress And Anxiety: 3 people, 8.33%
Pain: 3 people, 8.33%
Migraine (headache): 3 people, 8.33%
Back Pain: 3 people, 8.33%
Asthma: 3 people, 8.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.56%
Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 5.56%
Mood Swings (an extreme or rapid change in mood): 2 people, 5.56%
Joint Pain: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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