Zonisamide and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Cefazolin (cefazolin sodium). Common drug interactions include anaemia among females and nephritis interstitial among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Cefazolin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

On Aug, 12, 2026

13 people who take Zonisamide and Cefazolin together, and have interactions are studied.

Zonisamide and Cefazolin drug interactions.

What are the common drug interactions of Zonisamide and Cefazolin, by gender? *:

female:

Anaemia (lack of blood)
Pyrexia (fever)
Activities of daily living impaired
Altered state of consciousness (altered state of mind)
C-reactive protein increased
Clavicle fracture
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Disuse syndrome (deterioration of body systems as a result of prescribed or unavoidable inactivity)
Dry skin

male:

Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Cellulitis (infection under the skin)
C-reactive protein increased
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Clavicle fracture
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Eosinophil count increased

What are the common drug interactions of Zonisamide and Cefazolin, by age (0-1 to 60+)? *:

0-1:

Drug ineffective

2-9:

n/a

10-19:

n/a

20-29:

Activities of daily living impaired
Altered state of consciousness (altered state of mind)
Anaemia (lack of blood)
C-reactive protein increased
Clavicle fracture
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Disuse syndrome (deterioration of body systems as a result of prescribed or unavoidable inactivity)
Dry skin
Fall

30-39:

Cellulitis (infection under the skin)
Drug eruption (adverse drug reaction of the skin)
Pyrexia (fever)
Aspartate aminotransferase increased
Gout (uric acid crystals building up in the body)
Myopathy (a muscular disease in which the muscle fibres do not function)

40-49:

Altered state of consciousness (altered state of mind)
C-reactive protein increased
Clavicle fracture
Hypokalaemia (low potassium)
International normalised ratio increased
Pneumonia
Pruritus (severe itching of the skin)
Rectal prolapse (falling of rectum from normal place)

50-59:

Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Anuria (failure of the kidneys to produce urine)
Blood creatinine increased
Blood urea increased
Cardiac arrest
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Encephalopathy (functioning of the brain is affected by some agent or condition)

60+:

Anaemia (lack of blood)
Cerebral atrophy (decrement in size of brain)
Lip erosion (peeling off of lip)
Lip pain
Lip ulceration (ulcer of lip)
Oliguria (not enough urine)
Oral discomfort (pain or irritation in mouth)
Oropharyngeal candidiasis (fungal infection of oropharynx)
Oropharyngeal pain
Pruritus generalised (generalized itching)

What are the existing conditions these people have? *

Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 15.38%
C-Reactive Protein Increased: 2 people, 15.38%
Pain: 2 people, 15.38%
Lower Respiratory Tract Infection: 1 person, 7.69%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 1 person, 7.69%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.69%
Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 1 person, 7.69%
Birth Control: 1 person, 7.69%
Cerebral Atrophy (decrement in size of brain): 1 person, 7.69%
Constipation: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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