Zonisamide and Cozaar drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zonisamide (zonisamide) and Cozaar (losartan potassium). Common drug interactions include diplopia among females and convulsion among males.
The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Cozaar. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Zonisamide?
Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.
What is Cozaar?
Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.
11 people who take Zonisamide and Cozaar together, and have interactions are studied.

What are the common drug interactions of Zonisamide and Cozaar, by gender? *:
female:
- Diplopia (double vision)
- Dysarthria (speech disorder)
- Facial bones fracture (bone fracture of face)
- Fall
- Gait disturbance
- Hemiparesis (weakness on one side of the body)
- Incontinence (lack of moderation or self-control)
- Intervertebral disc degeneration (spinal disc degeneration)
- Intervertebral disc displacement
- Mobility decreased (ability to move is reduced)
male:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Death
What are the common drug interactions of Zonisamide and Cozaar, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
40-49:
- Neck pain
- Somnolence (a state of near-sleep, a strong desire for sleep)
50-59:
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Hemiparesis (weakness on one side of the body)
- Incontinence (lack of moderation or self-control)
- Intervertebral disc degeneration (spinal disc degeneration)
- Intervertebral disc displacement
- Memory impairment
- Mobility decreased (ability to move is reduced)
- Multiple system atrophy (degeneration of nerve cells in specific areas of the brain)
60+:
- Viral infection
What are the existing conditions these people have? *
- Depression: 4 people, 36.36%
- Type 2 Diabetes: 3 people, 27.27%
- Insomnia (sleeplessness): 3 people, 27.27%
- Blood Glucose Abnormal: 3 people, 27.27%
- Cellulitis (infection under the skin): 3 people, 27.27%
- Constipation: 3 people, 27.27%
- Diabetes: 3 people, 27.27%
- Dizziness: 3 people, 27.27%
- Headache (pain in head): 3 people, 27.27%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 27.27%
* Approximation only. Some reports may have incomplete information.
Do you take Zonisamide and Cozaar?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Zonisamide (11,445 reports)
- Cozaar (45,124 reports)
Browse all drug interactions of Zonisamide and Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zonisamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cozaar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zonisamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cozaar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
- Lai SW, Lin HF, Lin CL, Liao KF, "No association between losartan use and acute pancreatitis in hypertensive patients", Eur J Hosp Pharm, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on zonisamide and losartan potassium (the active ingredients of Zonisamide and Cozaar, respectively), and Zonisamide and Cozaar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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