Zonisamide and Diovan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Diovan (valsartan). Common drug interactions include bone disorder among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Diovan. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,154 Diovan users. Check the latest studies of Diovan.

On Aug, 09, 2026

65 people who take Zonisamide and Diovan together, and have interactions are studied.

Zonisamide and Diovan drug interactions.

What are the common drug interactions of Zonisamide and Diovan, by gender? *:

female:

Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Confusional state
Death
Drug hypersensitivity
Drug ineffective
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Gastric mucosal lesion (lesion of stomach mucous membrane)

male:

Alanine aminotransferase increased
Blood lactate dehydrogenase increased
Vascular insufficiency
Drug eruption (adverse drug reaction of the skin)
Pyrexia (fever)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Accident
Dysphagia (a condition in which swallowing is difficult or painful)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypercalcaemia (elevated calcium (ca+) level in the blood)

What are the common drug interactions of Zonisamide and Diovan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Inappropriate antidiuretic hormone secretion

50-59:

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
White blood cell count increased
Alopecia (absence of hair from areas of the body)
Cerebral haemorrhage (bleeding within the brain)
Hot flush (sudden feelings of heat)
Mycoplasma infection (bacterial infection)
Staphylococcal infection (an infection with staphylococcus bacteria)
Stress
Varicella
Alanine aminotransferase increased

60+:

Neuropathy peripheral (surface nerve damage)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Muscular weakness (muscle weakness)
Aphasia (damage to the parts of the brain that control language)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Urinary tract infection
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Frostbite (damage is caused to skin and other tissues due to freezing)
Haemorrhage (bleeding)
Laceration (tearing of soft body tissue)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 16.92%
Cerebral Haemorrhage (bleeding within the brain): 11 people, 16.92%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 9.23%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 9.23%
Diabetes: 6 people, 9.23%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 9.23%
Agitation (state of anxiety or nervous excitement): 6 people, 9.23%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 7.69%
Depression: 5 people, 7.69%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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