Zonisamide and Erythromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Erythromycin (erythromycin). Common drug interactions include nasal septum deviation among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Erythromycin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

On Jul, 12, 2026

17 people who take Zonisamide and Erythromycin together, and have interactions are studied.

Zonisamide and Erythromycin drug interactions.

What are the common drug interactions of Zonisamide and Erythromycin, by gender? *:

female:

Nasal septum deviation (deviated nasal septum)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephrolithiasis (calculi in the kidneys)
Arthralgia (joint pain)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Dry eye (lack of adequate tears)
Headache (pain in head)
Migraine with aura (headache with vision weakness)
Type 2 diabetes mellitus
Urinary tract infection

male:

Aggression
Irritability
Disease progression
Disease recurrence
Personality change
Apnoea (suspension of external breathing)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

What are the common drug interactions of Zonisamide and Erythromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Apnoea (suspension of external breathing)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Concomitant disease progression (progress in accompanying disease)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disease progression
Disease recurrence

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aggression
Irritability
Personality change

50-59:

Chronic kidney disease
Osteitis (a general term for inflammation of bone)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)
Osteonecrosis of jaw (death of bone of jaw)
Urinary tract infection
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Arthropathy

60+:

Arthralgia (joint pain)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Pain in extremity
Back pain
Fall
Asthenia (weakness)
Fatigue (feeling of tiredness)
Respiratory tract infection
Weight decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 29.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 29.41%
Pemphigoid (tense blisters on the skin): 4 people, 23.53%
Stress And Anxiety: 3 people, 17.65%
Insomnia (sleeplessness): 2 people, 11.76%
Back Pain: 2 people, 11.76%
Depression: 2 people, 11.76%
Diabetes: 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
High Blood Cholesterol: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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