Zonisamide and Oxybutynin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zonisamide (zonisamide) and Oxybutynin (oxybutynin). Common drug interactions include chronic kidney disease among females and abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Zonisamide and Oxybutynin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Oxybutynin?

Oxybutynin has active ingredients of oxybutynin. It is often used in urge incontinence. eHealthMe is studying from 23,143 Oxybutynin users. Check the latest studies of Oxybutynin.

On Jul, 04, 2026

53 people who take Zonisamide and Oxybutynin together, and have interactions are studied.

Zonisamide and Oxybutynin drug interactions.

What are the common drug interactions of Zonisamide and Oxybutynin, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Fatigue (feeling of tiredness)
Diarrhoea
Fall
Memory impairment
Balance disorder
Disturbance in attention
Visual impairment

male:

Abscess (pus)
Anal fistula
Gingivitis (inflammation of gums)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Nausea (feeling of having an urge to vomit)
Pain
Subcutaneous abscess
Tremor (trembling or shaking movements in one or more parts of your body)
Wound
Infection

What are the common drug interactions of Zonisamide and Oxybutynin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Decreased appetite
Fall
Fatigue (feeling of tiredness)
Memory impairment
Personality change
Visual impairment
Wrist fracture
Chronic kidney disease
Constipation
Diarrhoea

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Balance disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Disturbance in attention
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Memory impairment

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Balance disorder
Dysstasia (difficulty in standing)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Fall
Gait disturbance
Haematoma (collection of blood outside the blood vessels)
Periorbital haematoma (collection of blood around the eyes)

60+:

Chronic kidney disease
Diarrhoea
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Burning sensation
Cerebrospinal fluid leakage
Decreased appetite
Depressed mood
Dermatitis allergic (inflammation of the skin due allergic reaction)
Discomfort
Drug hypersensitivity

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 30.19%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 20.75%
High Blood Cholesterol: 10 people, 18.87%
Pain: 10 people, 18.87%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 18.87%
High Blood Pressure: 7 people, 13.21%
Depression: 7 people, 13.21%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 11.32%
Migraine (headache): 5 people, 9.43%
Diabetes: 5 people, 9.43%

* Approximation only. Some reports may have incomplete information.

Do you take Zonisamide and Oxybutynin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously