Zopiclone and Ascorbate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zopiclone (eszopiclone) and Ascorbate (vitamin c (ascorbic acid)). Common drug interactions include deep vein thrombosis postoperative among females.

The phase IV clinical study analyzes what interactions people have when they take Zopiclone and Ascorbate. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.

What is Ascorbate?

Ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,446 Ascorbate users. Check the latest studies of Ascorbate.



On Jul, 07, 2026

60 people who take Zopiclone and Ascorbate together, and have interactions are studied.

Zopiclone and Ascorbate drug interactions.

What are the common drug interactions of Zopiclone and Ascorbate, by gender? *:

female:

  1. Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)
  2. Drug ineffective
  3. Depression
  4. Drug intolerance (drug sensitivity)
  5. Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
  6. Grip strength decreased
  7. Wound infection
  8. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  9. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  10. Confusional state

male:

n/a

What are the common drug interactions of Zopiclone and Ascorbate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Asthma
  2. Back pain
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Coeliac disease (simple food intolerance)
  5. Constipation
  6. Drug hypersensitivity
  7. Drug ineffective
  8. Drug intolerance (drug sensitivity)
  9. Erythema (redness of the skin)
  10. Fatigue (feeling of tiredness)

40-49:

  1. Dyspepsia (indigestion)
  2. Fatigue (feeling of tiredness)
  3. Gait disturbance
  4. Migraine (headache)
  5. Breast cancer stage ii
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Respiratory disorder (respiratory disease)
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

50-59:

  1. Asthma
  2. Back pain
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Coeliac disease (simple food intolerance)
  5. Constipation
  6. Drug hypersensitivity
  7. Drug ineffective
  8. Drug intolerance (drug sensitivity)
  9. Erythema (redness of the skin)
  10. Fatigue (feeling of tiredness)

60+:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Frequent bowel movements
  4. Haematochezia (passage of stools containing blood)
  5. Headache (pain in head)
  6. Infusion related reaction
  7. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nausea (feeling of having an urge to vomit)
  10. Oral candidiasis (fungal infection of mouth)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 53 people, 88.33%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 37 people, 61.67%
  3. Stress And Anxiety: 21 people, 35.00%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 26.67%
  5. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 11 people, 18.33%
  6. Herpes Zoster: 10 people, 16.67%
  7. Pain: 5 people, 8.33%
  8. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 8.33%
  9. Indigestion: 5 people, 8.33%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zopiclone and Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zopiclone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ascorbate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone and vitamin c (ascorbic acid) (the active ingredients of Zopiclone and Ascorbate, respectively), and Zopiclone and Ascorbate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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