Zopiclone and Dayvigo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zopiclone (eszopiclone) and Dayvigo (lemborexant). Common drug interactions include drug eruption among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Zopiclone and Dayvigo. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,331 Zopiclone users. Check the latest studies of Zopiclone.

What is Dayvigo?

Dayvigo has active ingredients of lemborexant. It is often used in insomnia. eHealthMe is studying from 1,470 Dayvigo users. Check the latest studies of Dayvigo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

41 people who take Zopiclone and Dayvigo together, and have interactions are studied.

Zopiclone and Dayvigo drug interactions.

What are the common drug interactions of Zopiclone and Dayvigo, by gender? *:

female:

Drug eruption (adverse drug reaction of the skin)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Fistula (an abnormal connection or passageway between two)
Foot fracture
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Haematocrit decreased
Haemoglobin decreased
Localised infection (infection at the single location)
Neck pain

male:

Tremor (trembling or shaking movements in one or more parts of your body)
Abnormal faeces (abnormal stool)
Dehydration (dryness resulting from the removal of water)
Depression
Faeces hard
Fatigue (feeling of tiredness)
Headache (pain in head)
Influenza like illness
Infusion related reaction
Injection site pain

What are the common drug interactions of Zopiclone and Dayvigo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pyrexia (fever)
Urine output decreased
White blood cell count decreased
Completed suicide (act of taking one's own life)
Obesity (having too much body fat)
Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Sexually inappropriate behaviour
Therapeutic response decreased (less preventive response)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Diabetic hyperglycaemic coma (diabetic coma occurs when blood sugar gets too high and the body becomes severely dehydrated)
Drug eruption (adverse drug reaction of the skin)
Dysphagia (a condition in which swallowing is difficult or painful)
Interstitial lung disease
Platelet count decreased

60+:

Nausea (feeling of having an urge to vomit)
Cholangitis acute (rapid infection of bile duct)
Blood potassium decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Decreased appetite
Diarrhoea
Dizziness
Drug hypersensitivity
Fistula (an abnormal connection or passageway between two)

What are the existing conditions these people have? *

Sleep Disorder: 5 people, 12.20%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 12.20%
Procedural Pain: 5 people, 12.20%
Depression: 5 people, 12.20%
Dehydration (dryness resulting from the removal of water): 5 people, 12.20%
Bipolar Disorder (mood disorder): 5 people, 12.20%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 9.76%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 9.76%
Hepatocellular Carcinoma (liver cancer): 3 people, 7.32%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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