Zopiclone and Micafungin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zopiclone (eszopiclone) and Micafungin (micafungin sodium). Common drug interactions include drug level increased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Zopiclone and Micafungin. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,331 Zopiclone users. Check the latest studies of Zopiclone.

What is Micafungin?

Micafungin has active ingredients of micafungin sodium. eHealthMe is studying from 6,562 Micafungin users. Check the latest studies of Micafungin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

58 people who take Zopiclone and Micafungin together, and have interactions are studied.

Zopiclone and Micafungin drug interactions.

What are the common drug interactions of Zopiclone and Micafungin, by gender? *:

female:

  1. Drug level increased
  2. Anaemia (lack of blood)
  3. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Febrile neutropenia (fever with reduced white blood cells)
  7. Infection
  8. Liver disorder (liver diseases)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Oral candidiasis (fungal infection of mouth)

male:

  1. Pyrexia (fever)
  2. Blood culture positive
  3. Hypotension (abnormally low blood pressure)
  4. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  5. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  6. Blood creatine phosphokinase increased
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Generalised oedema (swelling all over the body)
  9. Multi-organ failure (multisystem organ failure)
  10. Muscular weakness (muscle weakness)

What are the common drug interactions of Zopiclone and Micafungin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Mucosal inflammation (infection of mucous membrane)

20-29:

  1. Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
  2. Diarrhoea
  3. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  4. Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
  5. Neutropenia (an abnormally low number of neutrophils)

30-39:

n/a

40-49:

  1. Abnormal behaviour
  2. Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
  3. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  4. Antithrombin iii decreased
  5. Blood bilirubin increased
  6. Cytomegalovirus test positive
  7. Disease recurrence
  8. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Herpes zoster

50-59:

  1. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  2. Blood creatine phosphokinase increased
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Generalised oedema (swelling all over the body)
  5. Multi-organ failure (multisystem organ failure)
  6. Muscular weakness (muscle weakness)
  7. Renal failure (kidney dysfunction)
  8. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  9. Pulmonary haemorrhage (acute bleeding from the lung)
  10. Drug level increased

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  3. Hypotension (abnormally low blood pressure)
  4. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  5. Abdominal pain
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  7. Abdominal distension
  8. Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypophagia (reduced food intake)

What are the existing conditions these people have? *

  1. Dyslipidaemia (abnormal amount of lipids): 23 people, 39.66%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 23 people, 39.66%
  3. Cardiac Amyloidosis (protein deposition in heart): 23 people, 39.66%
  4. Bone Marrow Conditioning Regimen: 6 people, 10.34%
  5. Febrile Neutropenia (fever with reduced white blood cells): 5 people, 8.62%
  6. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 8.62%
  7. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 8.62%
  8. Cough: 4 people, 6.90%
  9. Itching: 4 people, 6.90%
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zopiclone and Micafungin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Micafungin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zopiclone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Micafungin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone and micafungin sodium (the active ingredients of Zopiclone and Micafungin, respectively), and Zopiclone and Micafungin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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