Zortress and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zortress (everolimus) and Colace (docusate ). Common drug interactions include haemorrhage among females and malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Zortress and Colace. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Zortress?

Zortress has active ingredients of everolimus. eHealthMe is studying from 1,589 Zortress users. Check the latest studies of Zortress.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.



On Jul, 12, 2026

22 people who take Zortress and Colace together, and have interactions are studied.

Zortress and Colace drug interactions.

What are the common drug interactions of Zortress and Colace, by gender? *:

female:

  1. Haemorrhage (bleeding)
  2. Heart transplant rejection
  3. Immunosuppressant drug level increased
  4. Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
  5. Multi-organ failure (multisystem organ failure)
  6. Muscular weakness (muscle weakness)
  7. Myalgia (muscle pain)
  8. Nephropathy toxic (damage to kidney due to toxins)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Parainfluenzae virus infection

male:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Fall
  3. Osteomyelitis (infection of bone)
  4. Pain
  5. Purulent discharge (discharge that contains pus)
  6. Skin ulcer
  7. Swelling
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Cough

What are the common drug interactions of Zortress and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Brain injury
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)

40-49:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Concomitant disease progression (progress in accompanying disease)
  4. Erythema (redness of the skin)
  5. Localised infection (infection at the single location)
  6. Osteomyelitis (infection of bone)
  7. Pain
  8. Purulent discharge (discharge that contains pus)
  9. Skin ulcer
  10. Swelling

50-59:

  1. Chills (felling of cold)
  2. Disease progression
  3. Dyspepsia (indigestion)
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Epistaxis (bleed from the nose)
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Hypoxia (low oxygen in tissues)
  8. Infection
  9. Insomnia (sleeplessness)
  10. Lymphadenopathy (disease or enlargement of lymph nodes)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Cough
  4. Diarrhoea
  5. Face injury
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Hypotension (abnormally low blood pressure)
  8. Hypoxia (low oxygen in tissues)
  9. Muscular weakness (muscle weakness)
  10. Myalgia (muscle pain)

What are the existing conditions these people have? *

  1. Nausea And Vomiting: 3 people, 13.64%
  2. Nausea (feeling of having an urge to vomit): 3 people, 13.64%
  3. Hypertriglyceridaemia (excess of triglycerides in the blood): 3 people, 13.64%
  4. High Blood Pressure: 3 people, 13.64%
  5. Stress And Anxiety: 2 people, 9.09%
  6. Portal Hypertension (increase in the blood pressure within a system of veins called the portal venous system): 2 people, 9.09%
  7. Pain: 2 people, 9.09%
  8. Encephalopathy (functioning of the brain is affected by some agent or condition): 2 people, 9.09%
  9. Depression: 2 people, 9.09%
  10. Ascites (accumulation of fluid in the abdominal cavity): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zortress and Colace?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zortress and Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zortress:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zortress and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on everolimus and docusate (the active ingredients of Zortress and Colace, respectively), and Zortress and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: