Zosyn and Calcium lactate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zosyn (piperacillin sodium; tazobactam sodium) and Calcium lactate (calcium). Common drug interactions include alanine aminotransferase increased among females and urinary retention among males.

The phase IV clinical study analyzes what interactions people have when they take Zosyn and Calcium lactate. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Calcium lactate?

Calcium lactate has active ingredients of calcium. eHealthMe is studying from 1,682 Calcium lactate users. Check the latest studies of Calcium lactate.

On Jul, 12, 2026

12 people who take Zosyn and Calcium lactate together, and have interactions are studied.

Zosyn and Calcium lactate drug interactions.

What are the common drug interactions of Zosyn and Calcium Lactate, by gender? *:

female:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Cardiac failure
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Generalised oedema (swelling all over the body)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Injection site erythema (redness at injection site)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Urinary retention (the inability to completely or partially empty the bladder)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Febrile neutropenia (fever with reduced white blood cells)
Haematuria (presence of blood in urine)
Liver disorder (liver diseases)
Pyrexia (fever)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic kidney disease

What are the common drug interactions of Zosyn and Calcium Lactate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Liver disorder (liver diseases)
Pyrexia (fever)

40-49:

n/a

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Eye pain
Febrile neutropenia (fever with reduced white blood cells)
Haematuria (presence of blood in urine)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Oedema peripheral (superficial swelling)
Oesophageal rupture (break in oesophagus)
Pleural effusion (water on the lungs)
Rash
Relapsing fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea)
Spinal compression fracture (fracture due to spinal compression on bone)
Vomiting
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 58.33%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 6 people, 50.00%
Fever: 6 people, 50.00%
Insomnia (sleeplessness): 6 people, 50.00%
Transfusion Reaction (a serious problem that occurs after a patient receives a transfusion of blood): 5 people, 41.67%
Alanine Aminotransferase Increased: 5 people, 41.67%
Aspartate Aminotransferase Increased: 5 people, 41.67%
Bleeding Disorders: 5 people, 41.67%
Diarrhea: 5 people, 41.67%
Dry Eyes (lack of adequate tears): 5 people, 41.67%

* Approximation only. Some reports may have incomplete information.

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