Zosyn and Campath drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zosyn (piperacillin sodium; tazobactam sodium) and Campath (alemtuzumab). Common drug interactions include diarrhoea among females and renal failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Zosyn and Campath. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Campath?

Campath has active ingredients of alemtuzumab. eHealthMe is studying from 4,909 Campath users. Check the latest studies of Campath.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

21 people who take Zosyn and Campath together, and have interactions are studied.

Zosyn and Campath drug interactions.

What are the common drug interactions of Zosyn and Campath, by gender? *:

female:

  1. Diarrhoea
  2. Pyrexia (fever)
  3. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  6. Haematoma (collection of blood outside the blood vessels)
  7. Pleural effusion (water on the lungs)
  8. Septic shock (shock due to blood infection)
  9. Tooth abscess (pus formation in tooth)
  10. Abdominal pain

male:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  5. Renal tubular necrosis (death of kidney tubules)
  6. Sepsis syndrome (a clinical condition of blood infection)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Bacteraemia (presence of bacteria in the blood)
  9. Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
  10. Catheter site haemorrhage (bleeding at catheter site)

What are the common drug interactions of Zosyn and Campath, by age (0-1 to 60+)? *:

0-1:

  1. Blood creatinine increased
  2. Fluid overload (too much fluid in the blood)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

2-9:

  1. Pyrexia (fever)
  2. Septic shock (shock due to blood infection)
  3. Tooth abscess (pus formation in tooth)
  4. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  5. Diarrhoea
  6. Diarrhoea haemorrhagic (bloody diarrhoea)
  7. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  8. Haematoma (collection of blood outside the blood vessels)
  9. Pleural effusion (water on the lungs)

10-19:

n/a

20-29:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Diarrhoea

30-39:

n/a

40-49:

n/a

50-59:

  1. Pyrexia (fever)
  2. Coagulopathy (blood's ability to clot is impaired)
  3. Haemorrhage (bleeding)
  4. Hepatic failure (liver failure)
  5. Hypotension (abnormally low blood pressure)
  6. Hypoxia (low oxygen in tissues)
  7. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  8. Multi-organ failure (multisystem organ failure)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Renal failure acute (rapid kidney dysfunction)

60+:

  1. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Blood urea increased
  4. Cardiac failure congestive
  5. Confusional state
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  7. Cytomegalovirus test positive
  8. Disease progression
  9. Dizziness
  10. Feeling hot

What are the existing conditions these people have? *

  1. High Blood Pressure: 8 people, 38.10%
  2. Diabetes: 7 people, 33.33%
  3. Pain: 6 people, 28.57%
  4. Constipation: 6 people, 28.57%
  5. Anaemia (lack of blood): 5 people, 23.81%
  6. Leukopenia (less number of white blood cells in blood): 5 people, 23.81%
  7. Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 23.81%
  8. Stress And Anxiety: 5 people, 23.81%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 19.05%
  10. Fever: 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

Do you take Zosyn and Campath?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zosyn and Campath:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Campath:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zosyn and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Campath and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on piperacillin sodium; tazobactam sodium and alemtuzumab (the active ingredients of Zosyn and Campath, respectively), and Zosyn and Campath (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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