Zosyn and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zosyn (piperacillin sodium; tazobactam sodium) and Haloperidol (haloperidol). Common drug interactions include peripheral embolism among females and intra-abdominal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Zosyn and Haloperidol. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.

On Jul, 22, 2026

33 people who take Zosyn and Haloperidol together, and have interactions are studied.

Zosyn and Haloperidol drug interactions.

What are the common drug interactions of Zosyn and Haloperidol, by gender? *:

female:

Peripheral embolism (sudden interruption of blood flow to an organ or body part)
Peripheral ischaemia (impaired circulation to an extremity)
Peripheral vascular disorder
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Streptococcal sepsis (whole body inflammation by streptococcal)
Thrombocytopenia (decrease of platelets in blood)
Vascular insufficiency

male:

Intra-abdominal haemorrhage (intra-abdominal bleeding)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Anaemia (lack of blood)
Anal abscess
Anaphylactic reaction (serious allergic reaction)
Anti-platelet antibody positive
Aortic valve disease
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatine increased

What are the common drug interactions of Zosyn and Haloperidol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac arrest

30-39:

Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)
Endocarditis (inflammation in heart muscle)
Kidney transplant rejection
Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
Post procedural complication
Pseudobulbar palsy (inability to control facial movements (such as chewing and speaking))
Pyrexia (fever)

40-49:

Intra-abdominal haemorrhage (intra-abdominal bleeding)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Peritoneal disorder
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Acute respiratory failure
Anaemia (lack of blood)
Anaphylactic reaction (serious allergic reaction)
Body temperature increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Klebsiella infection
Nephritis allergic (inflammation of nephrons due to allergen)

60+:

Febrile neutropenia (fever with reduced white blood cells)
Renal failure acute (rapid kidney dysfunction)
Platelet count decreased
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Systemic candida (whole body fungal infection)
Systemic mycosis (fungal infections of the body)
Acute respiratory failure
Anal abscess
Anti-platelet antibody positive
Anxiety

What are the existing conditions these people have? *

Pneumonia: 4 people, 12.12%
Pain: 4 people, 12.12%
Immunodeficiency Disorders: 4 people, 12.12%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 3 people, 9.09%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 9.09%
Systemic Mycosis (fungal infections of the body): 2 people, 6.06%
Diabetes: 2 people, 6.06%
Agitation (state of anxiety or nervous excitement): 2 people, 6.06%
Aplastic Anemia: 2 people, 6.06%
Bacterial Sepsis: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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