Zyban and Fentanyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyban (bupropion hydrochloride) and Fentanyl (fentanyl citrate). Common drug interactions include bone disorder among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Zyban and Fentanyl. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Zyban?

Zyban has active ingredients of bupropion hydrochloride. It is often used in quit smoking. eHealthMe is studying from 8,029 Zyban users. Check the latest studies of Zyban.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

On Aug, 06, 2026

16 people who take Zyban and Fentanyl together, and have interactions are studied.

What are the common drug interactions of Zyban and Fentanyl, by gender? *:

female:

Bone disorder
Bone pain
Breast cancer metastatic
Culture positive
Dental fistula
Depressed level of consciousness
Drug ineffective
Faeces discoloured
Gastritis (inflammation of stomach)
General physical health deterioration (weak health status)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sudden death unexplained
Abnormal sensation in eye
Eye pain

What are the common drug interactions of Zyban and Fentanyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Breast lump (localized swelling that feels different from the surrounding breast tissue)
Breast neoplasm (non cancerous tumour of breast)
Crying
Decreased activity
Diarrhoea
Insomnia (sleeplessness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mood disorder (a condition characterized by distorted, excessive or inappropriate moods or emotions)
Sweat gland disorder

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sudden death unexplained
Abnormal sensation in eye
Eye pain
Injection site inflammation
Injection site pain
Rash erythematous (redness of the skin)

50-59:

Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Fatigue (feeling of tiredness)
Gait disturbance
Gastritis (inflammation of stomach)
General physical health deterioration (weak health status)
Hypersomnia (excessive daytime sleepiness (eds))
Hypokalaemia (low potassium)
Impaired healing
Influenza like illness

60+:

n/a

What are the existing conditions these people have? *

Oedema Peripheral (superficial swelling): 4 people, 25.00%
Insomnia (sleeplessness): 4 people, 25.00%
Gastric Ulcer (stomach ulcer): 4 people, 25.00%
Breast Cancer Metastatic: 4 people, 25.00%
Ascites (accumulation of fluid in the abdominal cavity): 4 people, 25.00%
Metastases To Bone (cancer spreads to bone): 3 people, 18.75%
Fatigue (feeling of tiredness): 3 people, 18.75%
Depression: 3 people, 18.75%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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