Zydelig and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zydelig (idelalisib) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include hypertension among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Zydelig and Valacyclovir. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Zydelig?

Zydelig has active ingredients of idelalisib. eHealthMe is studying from 1,909 Zydelig users. Check the latest studies of Zydelig.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 03, 2026

31 people who take Zydelig and Valacyclovir together, and have interactions are studied.

Zydelig and Valacyclovir drug interactions.

What are the common drug interactions of Zydelig and Valacyclovir, by gender? *:

female:

Hypertension (high blood pressure)
Infusion related reaction
Abdominal discomfort
Anaemia (lack of blood)
Blood pressure decreased
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysarthria (speech disorder)
Fall

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Respiratory moniliasis (fungal infection of respiratory system)
Angioedema (rapid swelling of the dermis)
Bladder transitional cell carcinoma (types of bladder cancer)
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Malaise (a feeling of general discomfort or uneasiness)
Neutropenia (an abnormally low number of neutrophils)
Second primary malignancy (after getting cure a cancer, a new cancer development)
Tendon rupture (tear of tendon)

What are the common drug interactions of Zydelig and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

50-59:

Bladder transitional cell carcinoma (types of bladder cancer)
Second primary malignancy (after getting cure a cancer, a new cancer development)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Ear infection
Infection
Lymphadenopathy (disease or enlargement of lymph nodes)
Respiratory moniliasis (fungal infection of respiratory system)
Angioedema (rapid swelling of the dermis)
Chemotherapy
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 20 people, 64.52%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 22.58%
Enlarged Prostate: 6 people, 19.35%
Pneumonia: 3 people, 9.68%
Pain: 3 people, 9.68%
Multiple Myeloma (cancer of the plasma cells): 3 people, 9.68%
Infection: 3 people, 9.68%
Immunodeficiency Common Variable: 3 people, 9.68%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 3 people, 9.68%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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