Zylet and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zylet (loteprednol etabonate; tobramycin) and Gabapentin (gabapentin). Common drug interactions include paranasal sinus discomfort among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Zylet and Gabapentin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Zylet?

Zylet has active ingredients of loteprednol etabonate; tobramycin. eHealthMe is studying from 493 Zylet users. Check the latest studies of Zylet.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

On Jul, 26, 2026

32 people who take Zylet and Gabapentin together, and have interactions are studied.

What are the common drug interactions of Zylet and Gabapentin, by gender? *:

female:

Paranasal sinus discomfort
Photophobia (extreme sensitivity to light)
Poor venous access
Chronic kidney disease
Renal failure (kidney dysfunction)
Colitis (inflammation of colon)
Cough
Diarrhoea
Nausea (feeling of having an urge to vomit)
Urinary tract infection

male:

Confusional state
Nausea (feeling of having an urge to vomit)
Death
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eye infection
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Infusion related reaction
Nephrogenic anaemia (anaemia due to kidney disease)
Rash pruritic (redness with itching)

What are the common drug interactions of Zylet and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

Chronic kidney disease
Decreased interest
Depression
Renal failure (kidney dysfunction)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Urate nephropathy (disease or abnormality of the kidney)

60+:

Nausea (feeling of having an urge to vomit)
Confusional state
Urinary tract infection
Visual impairment
Abdominal pain
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

High Blood Cholesterol: 9 people, 28.12%
High Blood Pressure: 9 people, 28.12%
Depression: 8 people, 25.00%
Insomnia (sleeplessness): 8 people, 25.00%
Nausea (feeling of having an urge to vomit): 8 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 21.88%
Back Pain: 7 people, 21.88%
Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 18.75%
Dry Mouth: 6 people, 18.75%
Hiv Infection: 6 people, 18.75%

* Approximation only. Some reports may have incomplete information.

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